NMT1 and ARL5A

Number of citations of the paper that reports this interaction (PubMedID 12414990)
0

Data Source:
HPRD (in vitro, in vivo)

		NMT1	ARL5A
Description		N-myristoyltransferase 1	ARF like GTPase 5A
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane	Cytoplasm Trans-Golgi Network
	Molecular Function	Glycylpeptide N-tetradecanoyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Peptidyl-lysine N6-myristoyltransferase Activity Myristoyltransferase Activity	Nucleotide Binding GTPase Activity GTP Binding
	Biological Process	In Utero Embryonic Development N-terminal Peptidyl-glycine N-myristoylation Regulation Of Opsin-mediated Signaling Pathway Cellular Response To Nutrient Levels Ketone Metabolic Process Protein Localization To Membrane Positive Regulation Of Protein Localization To Lysosome Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Positive Regulation Of TORC1 Signaling	Intracellular Protein Transport Vesicle-mediated Transport Protein Localization To Golgi Membrane
Pathways		Late Phase of HIV Life Cycle eNOS activation Inactivation, recovery and regulation of the phototransduction cascade Activation, myristolyation of BID and translocation to mitochondria
Drugs		(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone	Guanosine-5'-Diphosphate
Diseases
GWAS		Asthma ( 31619474) Blood glucose levels ( 31928498) Brain morphology (MOSTest) ( 32665545) Craniofacial microsomia ( 26853712) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Multisite chronic pain ( 31194737 33830993) Periventricular white matter hyperintensities ( 32517579) Plateletcrit ( 32888494) Pulse pressure ( 30578418) Systolic blood pressure ( 31928498 30578418) Walking pace ( 33128006) White matter hyperintensities ( 32358547) White matter hyperintensity volume ( 33293549)	Response to cognitive-behavioural therapy in anxiety disorder ( 26989097)
Interacting Genes		14 interacting genes: ANXA13 ARL5A CABP1 CABP2 CAPN2 CSNK2A1 FYN GNAZ HPCA LYN MARCKS NOS3 SRC TP53	6 interacting genes: APP CBX1 CBX3 CBX5 KPNA2 NMT1
Entrez ID		4836	26225
HPRD ID		01187	12343
Ensembl ID		ENSG00000136448	ENSG00000162980
Uniprot IDs		P30419	Q9Y689
PDB IDs		1RXT 3IU1 3IU2 3IWE 3JTK 4C2Y 4C2Z 5MU6 5NPQ 5O6H 5O6J 5O9S 5O9T 5O9U 5O9V 5UUT 6EHJ 6F56 6FZ2 6FZ3 6FZ5 6PAV 6QRM 6SJZ 6SK2 6SK3 6SK8 6SKJ 7OWM 7OWN 7OWO 7OWP 7OWQ 7OWR 7OWU 7RK3 8Q23 8Q24 8Q26 8Q2Z 8Q3D 8Q3S 8Q3T	1Z6Y 1ZJ6 2H16 2H17
Enriched GO Terms of Interacting Partners?		Membrane Raft Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Stimulatory C-type Lectin Receptor Signaling Pathway Scaffold Protein Binding Cellular Response To Lectin Fc Receptor Mediated Stimulatory Signaling Pathway Ephrin Receptor Binding Regulation Of Cellular Localization Response To Amino Acid Negative Regulation Of Inflammatory Response To Antigenic Stimulus Fc-gamma Receptor Signaling Pathway Regulation Of Protein Localization Response To Fluid Shear Stress Non-membrane Spanning Protein Tyrosine Kinase Activity T Cell Costimulation Regulation Of Transport Ephrin Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Regulation Of Apoptotic Signaling Pathway Enzyme Binding Fc Receptor Signaling Pathway Signaling Receptor Activator Activity Cellular Response To L-glutamate Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Phospholipase Activator Activity Cellular Response To Amino Acid Stimulus Cellular Response To Oxygen-containing Compound Positive Regulation Of Protein Localization To Membrane Regulation Of Establishment Of Protein Localization Regulation Of Apoptotic Process Plasma Membrane Regulation Of Programmed Cell Death Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Response To Hydrogen Peroxide DNA Damage Checkpoint Signaling Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Cytoplasm Negative Regulation Of Cell Communication Negative Regulation Of Signaling Autophagy Calcium Ion Binding Perinuclear Endoplasmic Reticulum Cellular Response To Stress Response To L-glutamate Lymphocyte Proliferation Mononuclear Cell Proliferation Negative Regulation Of Protein Transport Phospholipase Binding Cellular Response To Platelet-derived Growth Factor Stimulus	Pericentric Heterochromatin Site Of DNA Damage Heterochromatin Epigenetic Regulation Of Gene Expression Chromocenter Chromatin Binding Heterochromatin Formation Histone Methyltransferase Binding Chromosome, Centromeric Region Negative Regulation Of Gene Expression, Epigenetic Chromosome, Telomeric Region Chromatin Remodeling Chromatin Organization Amyloid-beta Complex Growth Cone Lamellipodium Negative Regulation Of Gene Expression Enzyme Binding Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Myristoyltransferase Activity Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Endothelin Production Negative Regulation Of RNA Metabolic Process Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Histone Deacetylase Binding Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin Glycylpeptide N-tetradecanoyltransferase Activity Peptidyl-lysine N6-myristoyltransferase Activity N-terminal Peptidyl-glycine N-myristoylation Chromatin Lock Complex Regulation Of G Protein-coupled Receptor Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response
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