NFATC3 and TTF1

Number of citations of the paper that reports this interaction (PMID 15173172)
19

Data Source:
HPRD (in vivo)

		NFATC3	TTF1
Gene Name		nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	transcription termination factor, RNA polymerase I
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Protein Binding	DNA Binding Chromatin Binding
	Biological Process	Patterning Of Blood Vessels Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Inflammatory Response Heart Development Fc-epsilon Receptor Signaling Pathway Innate Immune Response Cellular Respiration Positive Regulation Of Transcription From RNA Polymerase II Promoter Smooth Muscle Cell Differentiation Muscle Cell Development Cellular Response To Calcium Ion Cellular Response To Lithium Ion	Chromatin Remodeling DNA-templated Transcription, Termination Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Negative Regulation Of DNA Replication Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways		Fc epsilon receptor (FCERI) signaling FCERI mediated Ca+2 mobilization Innate Immune System	NoRC negatively regulates rRNA expression RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CDK6 CSNK1A1 FOS MAPK8 MAPK9 TTF1	6 interactors: BAZ2A KAT2B NFATC3 PTRF SMAD1 SMAD7
Entrez ID		4775	7270
HPRD ID		04077	02866
Ensembl ID		ENSG00000072736	ENSG00000125482
Uniprot IDs		B5B2S0 B5B2S1 B5B2S3 B5B2S4 I3L3K7 Q12968	Q15361
PDB IDs		2XRW 2XS0
Enriched GO Terms of Interacting Partners?		Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway JUN Phosphorylation Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Regulation Of Circadian Rhythm Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Phosphate-containing Compound Metabolic Process Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Gene Expression Positive Regulation Of Innate Immune Response Response To Other Organism Response To Biotic Stimulus Response To Mechanical Stimulus Response To External Stimulus MAPK Cascade Fc-epsilon Receptor Signaling Pathway Phosphorylation Regulation Of Innate Immune Response Fc Receptor Signaling Pathway Signal Transduction By Phosphorylation Response To Lipopolysaccharide Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Metal Ion Response To Molecule Of Bacterial Origin Response To Light Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Cadmium Ion Regulation Of Immune System Process Response To Radiation Protein Phosphorylation Hippocampus Development Immune Response-regulating Signaling Pathway Response To Inorganic Substance Regulation Of Cell Morphogenesis Response To Bacterium Signaling JNK Cascade Cell Communication	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase I Promoter Histone H3-K9 Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated BMP Signaling Pathway Nitrogen Compound Metabolic Process Heart Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Heterochromatin Assembly Involved In Chromatin Silencing Gene Silencing Positive Regulation Of Cellular Biosynthetic Process Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Tissue Morphogenesis Mesonephros Development Regulation Of Transcription From RNA Polymerase II Promoter Tube Development Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Transforming Growth Factor Beta Receptor Signaling Pathway Kidney Epithelium Development N-terminal Peptidyl-lysine Acetylation Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Transforming Growth Factor Beta Stimulus Chromatin Remodeling Cardiovascular System Development Response To Transforming Growth Factor Beta Cardiac Muscle Tissue Development
Tagcloud ?		acting aortic basally cardiomyocyte cardiomyocytes complimentary concert constriction coupled desensitize exaggerated exert facilitator failing grk2 grk5 grks hypertrophic hypertrophy maladaptive myocardium myocytes nucleus participates phenylephrine rationale reside transverse	able activate binds cotransfection differentiation essential experiments finding hormone importance main maintenance markers minimal modulation mutated nonthyroid promoter promoters shows step strengthens thyroglobulin thyroid thyroperoxidase trans transcription tsh tshr
Tagcloud (Difference) ?		acting aortic basally cardiomyocyte cardiomyocytes complimentary concert constriction coupled desensitize exaggerated exert facilitator failing grk2 grk5 grks hypertrophic hypertrophy maladaptive myocardium myocytes nucleus participates phenylephrine rationale reside transverse	able activate binds cotransfection differentiation essential experiments finding hormone importance main maintenance markers minimal modulation mutated nonthyroid promoter promoters shows step strengthens thyroglobulin thyroid thyroperoxidase trans transcription tsh tshr
Tagcloud (Intersection) ?