LYL1

Gene Name		lymphoblastic leukemia associated hematopoiesis regulator 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	DNA Binding Protein Binding Protein Dimerization Activity
	Biological Process	Blood Vessel Maturation Transcription, DNA-templated Regulation Of Transcription, DNA-templated B Cell Differentiation Positive Regulation Of Transcription, DNA-templated Definitive Hemopoiesis
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: DRG1 LMO1 LMO2 NFKB1 NFKBIA TCF3 TCF4
Entrez ID		4066
HPRD ID		01046
Ensembl ID		ENSG00000104903
Uniprot IDs		P12980
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cholesterol Transport Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Wnt Signaling Pathway Regulation Of Macrophage Derived Foam Cell Differentiation Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Immune System Process Regulation Of Lipid Storage Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Negative Regulation Of Transcription, DNA-templated TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Somatic Stem Cell Maintenance RNA Biosynthetic Process MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Type I Interferon Production Regulation Of RNA Biosynthetic Process Toll-like Receptor 4 Signaling Pathway Response To Organic Substance Regulation Of RNA Metabolic Process Negative Regulation Of Myeloid Cell Differentiation Response To Bacterium Regulation Of Immune System Process Negative Regulation Of Gene Expression Negative Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Biosynthetic Process
Tagcloud ?		alter box canntg consensus cos discrimination e12 e2a exclusively flanking helix hlh homology influenced initially lymphoblastic mitogen motif oncoprotein positioned residue ser122 ser172 serine sharing subcellular tal1 termed unaffected