LYL1

Description		LYL1 basic helix-loop-helix family member
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity
	Biological Process	Blood Vessel Maturation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II B Cell Differentiation Positive Regulation Of DNA-templated Transcription Definitive Hemopoiesis
Pathways		NGF-stimulated transcription
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Brain morphology (MOSTest) ( 32665545) Cognitive ability (MTAG) ( 29186694) Household income ( 31844048) Household income (MTAG) ( 31844048) Mean reticulocyte volume ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Plateletcrit ( 32888494) Refractive error ( 32231278)
Novel Interacting Genes		2 novel interacting genes: BRD4 TSSK6
Interacting Genes		8 interacting genes: DRG1 LMO1 LMO2 NFKB1 NFKBIA RHOU TCF3 TCF4
Entrez ID		4066
HPRD ID		01046
Ensembl ID		ENSG00000104903
Uniprot IDs		P12980
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription By RNA Polymerase II I-kappaB/NF-kappaB Complex Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Transcription Regulator Complex Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Binding Regulation Of Transcription By RNA Polymerase II BHLH Transcription Factor Binding Response To Muscle Stretch Positive Regulation Of Biosynthetic Process Regulation Of Macrophage Derived Foam Cell Differentiation Non-canonical NF-kappaB Signal Transduction Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Lipid Storage Protein Sequestering Activity Negative Regulation Of Cytokine Production Involved In Inflammatory Response Response To DsRNA Positive Regulation Of Macromolecule Metabolic Process Transcription Coactivator Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transcription Cis-regulatory Region Binding B Cell Receptor Signaling Pathway Canonical NF-kappaB Signal Transduction E-box Binding Tumor Necrosis Factor-mediated Signaling Pathway Histone H4K8ac Reader Activity Positive Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Cholesterol Transport Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Nucleus Regulation Of Immune System Process Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of DNA-templated Transcription Initiation NF-kappaB P50/p65 Complex Positive Regulation Of Cell Differentiation Regulation Of Cell Differentiation Regulation Of Developmental Process Histone H3K9ac Reader Activity Histone H4K5ac Reader Activity Histone H4K12ac Reader Activity Axonemal Microtubule Doublet Inner Sheath Positive Regulation Of Neuron Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process
Tagcloud ?