NDUFB8 and ATP6V0D2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NDUFB8	ATP6V0D2
Gene Name		NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Endoplasmic Reticulum Integral Component Of Membrane	Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Extracellular Vesicular Exosome
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity	Protein Binding Hydrogen Ion Transmembrane Transporter Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process	Cellular Iron Ion Homeostasis Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Transferrin Transport Interaction With Host Transmembrane Transport Phagosome Maturation
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport	Phagosomal maturation (early endosomal stage) Iron uptake and transport Latent infection of Homo sapiens with Mycobacterium tuberculosis Transferrin endocytosis and recycling Insulin receptor recycling Signaling by Insulin receptor
Drugs		NADH
Diseases
GWAS		Palmitoleic acid (16:1n-7) plasma levels ( 23362303)	Adverse response to lamotrigine and phenytoin ( 22379998)
Protein-Protein Interactions		6 interactors: ATP6V0D2 CACNA1A EIF2B3 PFN2 PIM2 ZAP70	5 interactors: ADRM1 AGO3 NDUFB8 RBM15B RPS3
Entrez ID		4714	245972
HPRD ID		11886	16522
Ensembl ID		ENSG00000166136	ENSG00000147614
Uniprot IDs		O95169	Q8N8Y2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Neurotransmitter Secretion Cerebellar Molecular Layer Development Vestibular Nucleus Development Beta Selection Regulation Of Exocytosis Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Gamma-aminobutyric Acid Secretion Protein Autophosphorylation Regulation Of Acetylcholine Secretion, Neurotransmission Rhythmic Synaptic Transmission Negative Regulation Of Ruffle Assembly Negative Regulation Of Translational Initiation In Response To Stress Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Negative Regulation Of Translation In Response To Stress Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Regulation Of Synaptic Transmission Positive Thymic T Cell Selection Negative Regulation Of Hormone Biosynthetic Process Regulation Of Translational Initiation In Response To Stress Pons Development Regulation Of Signaling Regulation Of Vesicle-mediated Transport Negative Thymic T Cell Selection Positive Regulation Of Alpha-beta T Cell Proliferation Cerebellar Purkinje Cell Differentiation Negative T Cell Selection Regulation Of Translation In Response To Stress Cellular Metal Ion Homeostasis Cerebellar Purkinje Cell Layer Morphogenesis Regulation Of Ruffle Assembly T Cell Migration Negative Regulation Of Translational Initiation Cellular Cation Homeostasis Cellular Ion Homeostasis Response To Peptide Hormone Posttranscriptional Regulation Of Gene Expression Reflex Metal Ion Homeostasis Behavioral Response To Pain Thymic T Cell Selection Regulation Of Cell Projection Organization Response To Peptide Neuromuscular Synaptic Transmission	MRNA Metabolic Process Positive Regulation Of DNA N-glycosylase Activity Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process MRNA Catabolic Process Cellular Nitrogen Compound Metabolic Process RNA Catabolic Process Nitrogen Compound Metabolic Process Translational Initiation Regulation Of Translation RNA Metabolic Process Negative Regulation Of DNA Repair Negative Regulation Of Translation Involved In Gene Silencing By MiRNA Gene Expression Proteasome Assembly Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cytoplasmic Translation Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Protein Metabolic Process Viral Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Protein Metabolic Process Biosynthetic Process Translation Gene Silencing By MiRNA Transcription, DNA-templated Posttranscriptional Gene Silencing RNA Biosynthetic Process Mitochondrial Electron Transport, NADH To Ubiquinone
Tagcloud ?			chip dcstamp demonstrates elucidate epigenetic epigenetically fusion h3k27me3 h3k4me3 lineage lysine macrophage modification monocyte multinucleated nfat ocstamp osteoclast osteoclastogenesis osteoclasts pcdh7 protocadherin rankl resorb seq sequencing silenced transcriptionally trimethylation
Tagcloud (Difference) ?			chip dcstamp demonstrates elucidate epigenetic epigenetically fusion h3k27me3 h3k4me3 lineage lysine macrophage modification monocyte multinucleated nfat ocstamp osteoclast osteoclastogenesis osteoclasts pcdh7 protocadherin rankl resorb seq sequencing silenced transcriptionally trimethylation
Tagcloud (Intersection) ?