SP110 and NAP1L2

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		SP110	NAP1L2
Gene Name		SP110 nuclear body protein	nucleosome assembly protein 1-like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus	Nucleus
	Molecular Function	DNA Binding Chromatin Binding Signal Transducer Activity Zinc Ion Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Signal Transduction Viral Process	Nucleosome Assembly Positive Regulation Of Neuron Differentiation Positive Regulation Of Histone H3-K14 Acetylation Regulation Of Stem Cell Division Positive Regulation Of Histone H3-K9 Acetylation
Pathways
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 18758461) Obesity-related traits ( 23251661)
Protein-Protein Interactions		11 interactors: ANXA7 CDKN1A NAP1L2 NDUFV2 OSGEP RUNX3 SMN1 TK1 TSC22D1 TTR ZSCAN9	2 interactors: PPP3R1 SP110
Entrez ID		3431	4674
HPRD ID		06832	02066
Ensembl ID		ENSG00000135899	ENSG00000186462
Uniprot IDs		G5E9C0 Q9HB58	Q9ULW6
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoside Metabolic Process Fetal Process Involved In Parturition Positive Regulation Of Histone H3-K14 Acetylation Threonylcarbamoyladenosine Biosynthetic Process Skeletal Muscle Cell Proliferation Cellular Metabolic Process Regulation Of Histone H3-K14 Acetylation Nucleobase-containing Compound Metabolic Process Digestive Tract Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Maturation Digestive System Development Positive Regulation Of Programmed Cell Death Threonylcarbamoyladenosine Metabolic Process Thyroid Hormone Transport Intestinal Epithelial Cell Maturation Anatomical Structure Development Response To Glucocorticoid Positive Regulation Of Cell Death Response To Corticosteroid Cellular Nitrogen Compound Metabolic Process Response To Cortisol Thymidine Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Response To Toxic Substance Regulation Of Stem Cell Division Positive Regulation Of Histone H3-K9 Acetylation Cellular Response To UV-B Deoxyribonucleoside Monophosphate Biosynthetic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Developmental Process Nitrogen Compound Metabolic Process	Positive Regulation Of NFAT Protein Import Into Nucleus Calcineurin-NFAT Signaling Cascade Inositol Phosphate-mediated Signaling Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Transcription Factor Import Into Nucleus
Tagcloud ?		cavitary cc classification ct dimensionality employed except explore fresh gc genotype heterozygous homozygous instead mtb multifactor mybbp1a mycobacterium pathological progress promising ptb rela rs3809849 rs9061 rs9905742 tree tuberculosis whole	1c acetylated acetylation assembly associates cdkn1c chromatin correlates defects deficiencies differentiating downregulation establishment h3k9 h4 histones idea interacts maintenance marked mediate modification neural neurogenesis neuronal normally nucleosome permissive tube
Tagcloud (Difference) ?		cavitary cc classification ct dimensionality employed except explore fresh gc genotype heterozygous homozygous instead mtb multifactor mybbp1a mycobacterium pathological progress promising ptb rela rs3809849 rs9061 rs9905742 tree tuberculosis whole	1c acetylated acetylation assembly associates cdkn1c chromatin correlates defects deficiencies differentiating downregulation establishment h3k9 h4 histones idea interacts maintenance marked mediate modification neural neurogenesis neuronal normally nucleosome permissive tube
Tagcloud (Intersection) ?