SP110 and OSGEP

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SP110	OSGEP
Gene Name		SP110 nuclear body protein	O-sialoglycoprotein endopeptidase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus	EKC/KEOPS Complex Nucleus Cytoplasm
	Molecular Function	DNA Binding Chromatin Binding Signal Transducer Activity Zinc Ion Binding	Transferase Activity, Transferring Acyl Groups Other Than Amino-acyl Groups Metal Ion Binding
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Signal Transduction Viral Process	Threonylcarbamoyladenosine Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 18758461) Obesity-related traits ( 23251661)
Protein-Protein Interactions		11 interactors: ANXA7 CDKN1A NAP1L2 NDUFV2 OSGEP RUNX3 SMN1 TK1 TSC22D1 TTR ZSCAN9	23 interactors: C19orf60 CIAPIN1 CRIP2 EMCN GP1BA HPS6 LENG1 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 SF3B3 SHC1 SP110 SPRED1 TNS1 WDR82 WIZ ZNF579 ZNF775
Entrez ID		3431	55644
HPRD ID		06832	10133
Ensembl ID		ENSG00000135899	ENSG00000092094
Uniprot IDs		G5E9C0 Q9HB58	Q9NPF4
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoside Metabolic Process Fetal Process Involved In Parturition Positive Regulation Of Histone H3-K14 Acetylation Threonylcarbamoyladenosine Biosynthetic Process Skeletal Muscle Cell Proliferation Cellular Metabolic Process Regulation Of Histone H3-K14 Acetylation Nucleobase-containing Compound Metabolic Process Digestive Tract Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Maturation Digestive System Development Positive Regulation Of Programmed Cell Death Threonylcarbamoyladenosine Metabolic Process Thyroid Hormone Transport Intestinal Epithelial Cell Maturation Anatomical Structure Development Response To Glucocorticoid Positive Regulation Of Cell Death Response To Corticosteroid Cellular Nitrogen Compound Metabolic Process Response To Cortisol Thymidine Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Response To Toxic Substance Regulation Of Stem Cell Division Positive Regulation Of Histone H3-K9 Acetylation Cellular Response To UV-B Deoxyribonucleoside Monophosphate Biosynthetic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Developmental Process Nitrogen Compound Metabolic Process	Regulation Of Cellular Ketone Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle Process
Tagcloud ?		cavitary cc classification ct dimensionality employed except explore fresh gc genotype heterozygous homozygous instead mtb multifactor mybbp1a mycobacterium pathological progress promising ptb rela rs3809849 rs9061 rs9905742 tree tuberculosis whole	ancient antigen associate bc biochemically box characterizing cul2 cullin2 deeper e3 ekc interactome keops lage3 ligase link melanoma mined oncogenesis oncoprotein orthologues overexpressed prame preferentially recruits reveal ubiquitin understood
Tagcloud (Difference) ?		cavitary cc classification ct dimensionality employed except explore fresh gc genotype heterozygous homozygous instead mtb multifactor mybbp1a mycobacterium pathological progress promising ptb rela rs3809849 rs9061 rs9905742 tree tuberculosis whole	ancient antigen associate bc biochemically box characterizing cul2 cullin2 deeper e3 ekc interactome keops lage3 ligase link melanoma mined oncogenesis oncoprotein orthologues overexpressed prame preferentially recruits reveal ubiquitin understood
Tagcloud (Intersection) ?