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PPP1R12A and ATXN10
Number of citations of the paper that reports this interaction (PMID
16498633
)
5
Data Source:
BioGRID
(two hybrid)
PPP1R12A
ATXN10
Gene Name
protein phosphatase 1, regulatory subunit 12A
ataxin 10
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Kinetochore
Nucleoplasm
Cytoplasm
Centrosome
Focal Adhesion
Actin Cytoskeleton
Contractile Fiber
PTW/PP1 Phosphatase Complex
Extracellular Space
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Dendrite
Neuronal Cell Body
Perinuclear Region Of Cytoplasm
Molecular Function
Enzyme Inhibitor Activity
Signal Transducer Activity
Protein Binding
Phosphatase Regulator Activity
Protein Kinase Binding
14-3-3 Protein Binding
Protein Binding
Identical Protein Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Protein Dephosphorylation
Mitotic Nuclear Division
Signal Transduction
Regulation Of Cell Adhesion
Regulation Of Myosin-light-chain-phosphatase Activity
Negative Regulation Of Catalytic Activity
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nucleocytoplasmic Transport
Centrosome Organization
Nervous System Development
Neuron Projection Development
Pathways
G2/M Transition
Mitotic G2-G2/M phases
Regulation of PLK1 Activity at G2/M Transition
Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Thiazide-induced adverse metabolic effects in hypertensive patients (
23400010
)
Protein-Protein Interactions
12 interactors:
ATXN10
DMPK
IL16
ILK
KDM1A
MPRIP
PRKG1
RHOA
ROCK1
ROCK2
SETD7
YWHAG
8 interactors:
ABCA1
FN1
GLS
GNB1
GNB2
GOLGA1
MRPS16
PPP1R12A
Entrez ID
4659
25814
HPRD ID
03606
04624
Ensembl ID
ENSG00000058272
ENSG00000130638
Uniprot IDs
B2RAH5
O14974
Q9UBB4
PDB IDs
2KJY
Enriched GO Terms of Interacting Partners
?
Neuron Projection Development
Nervous System Development
Regulation Of Organelle Organization
Generation Of Neurons
Regulation Of Cell Differentiation
Neuron Development
Rho Protein Signal Transduction
Neurogenesis
Regulation Of Stress Fiber Assembly
Cell Development
Neuron Differentiation
Cell Projection Organization
Regulation Of Locomotion
Locomotion
Ephrin Receptor Signaling Pathway
Organelle Organization
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Actin Cytoskeleton Organization
Regulation Of Cell-matrix Adhesion
Cell Differentiation
Cell Migration
Movement Of Cell Or Subcellular Component
Regulation Of Actin Filament-based Process
Blood Coagulation
Cell Motility
Hemostasis
Regulation Of Cytoskeleton Organization
Intracellular Signal Transduction
Regulation Of Keratinocyte Differentiation
Regulation Of Cell-substrate Adhesion
System Development
Regulation Of Cellular Component Organization
Regulation Of Body Fluid Levels
Wound Healing
Chemotaxis
Ras Protein Signal Transduction
Actin Cytoskeleton Organization
Regulation Of Establishment Of Cell Polarity
Regulation Of Cell Adhesion
Regulation Of Cell Motility
Regulation Of Establishment Or Maintenance Of Cell Polarity
Neuron Projection Morphogenesis
Actin Filament-based Process
Cellular Protein Modification Process
Protein Phosphorylation
Regulation Of Epidermal Cell Differentiation
Regulation Of Cellular Component Movement
Muscle System Process
Response To Wounding
Regulation Of Focal Adhesion Assembly
Cellular Response To Glucagon Stimulus
Response To Glucagon
Secretion By Cell
Synaptic Transmission
Energy Reserve Metabolic Process
Secretion
Regulation Of Myosin-light-chain-phosphatase Activity
Calcium-independent Cell-matrix Adhesion
Interleukin-1 Beta Secretion
Cellular Response To Acid Chemical
Platelet Activation
Glutamine Catabolic Process
Apolipoprotein A-I-mediated Signaling Pathway
Interleukin-1 Secretion
Glutamate Biosynthetic Process
Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Cholesterol Storage
High-density Lipoprotein Particle Assembly
Muscle Cell Apoptotic Process
Establishment Of Localization In Cell
Cell-cell Signaling
Intracellular Cholesterol Transport
Intracellular Sterol Transport
Phospholipid Homeostasis
Platelet Dense Granule Organization
Integrin Activation
Phospholipid Efflux
Phagocytosis, Engulfment
Energy Derivation By Oxidation Of Organic Compounds
Regulation Of Respiratory Gaseous Exchange By Neurological System Process
Response To Low-density Lipoprotein Particle
Interleukin-1 Beta Production
Cellular Response To Prostaglandin E Stimulus
Cellular Response To Peptide Hormone Stimulus
Small Molecule Metabolic Process
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Cellular Response To Peptide
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Regulation Of Respiratory System Process
Cellular Localization
G-protein Coupled Receptor Signaling Pathway
Cellular Response To Cholesterol
Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Reverse Cholesterol Transport
Response To Laminar Fluid Shear Stress
Membrane Invagination
Protein-lipid Complex Assembly
Response To Lipoprotein Particle
Cellular Response To Sterol
Positive Regulation Of Cholesterol Efflux
Tagcloud
?
adca
adcas
arca
ascertained
ataxia
ataxias
attct
connections
cypriot
depended
drpla
encompass
geographical
hereby
pentanucleotide
rarer
repeat
sca
sca1
sca10
sca12
sca17
sca2
sca3
sca6
sca7
sca8
scas
triplet
Tagcloud (Difference)
?
adca
adcas
arca
ascertained
ataxia
ataxias
attct
connections
cypriot
depended
drpla
encompass
geographical
hereby
pentanucleotide
rarer
repeat
sca
sca1
sca10
sca12
sca17
sca2
sca3
sca6
sca7
sca8
scas
triplet
Tagcloud (Intersection)
?