PPP1R12A and ATXN10

Number of citations of the paper that reports this interaction (PMID 16498633)
5

Data Source:
BioGRID (two hybrid)

		PPP1R12A	ATXN10
Gene Name		protein phosphatase 1, regulatory subunit 12A	ataxin 10
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Nucleoplasm Cytoplasm Centrosome Focal Adhesion Actin Cytoskeleton Contractile Fiber PTW/PP1 Phosphatase Complex	Extracellular Space Cytoplasm Cytosol Plasma Membrane Membrane Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Enzyme Inhibitor Activity Signal Transducer Activity Protein Binding Phosphatase Regulator Activity Protein Kinase Binding 14-3-3 Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Dephosphorylation Mitotic Nuclear Division Signal Transduction Regulation Of Cell Adhesion Regulation Of Myosin-light-chain-phosphatase Activity Negative Regulation Of Catalytic Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleocytoplasmic Transport Centrosome Organization	Nervous System Development Neuron Projection Development
Pathways		G2/M Transition Mitotic G2-G2/M phases Regulation of PLK1 Activity at G2/M Transition Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Protein-Protein Interactions		12 interactors: ATXN10 DMPK IL16 ILK KDM1A MPRIP PRKG1 RHOA ROCK1 ROCK2 SETD7 YWHAG	8 interactors: ABCA1 FN1 GLS GNB1 GNB2 GOLGA1 MRPS16 PPP1R12A
Entrez ID		4659	25814
HPRD ID		03606	04624
Ensembl ID		ENSG00000058272	ENSG00000130638
Uniprot IDs		B2RAH5 O14974	Q9UBB4
PDB IDs		2KJY
Enriched GO Terms of Interacting Partners?		Neuron Projection Development Nervous System Development Regulation Of Organelle Organization Generation Of Neurons Regulation Of Cell Differentiation Neuron Development Rho Protein Signal Transduction Neurogenesis Regulation Of Stress Fiber Assembly Cell Development Neuron Differentiation Cell Projection Organization Regulation Of Locomotion Locomotion Ephrin Receptor Signaling Pathway Organelle Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Actin Cytoskeleton Organization Regulation Of Cell-matrix Adhesion Cell Differentiation Cell Migration Movement Of Cell Or Subcellular Component Regulation Of Actin Filament-based Process Blood Coagulation Cell Motility Hemostasis Regulation Of Cytoskeleton Organization Intracellular Signal Transduction Regulation Of Keratinocyte Differentiation Regulation Of Cell-substrate Adhesion System Development Regulation Of Cellular Component Organization Regulation Of Body Fluid Levels Wound Healing Chemotaxis Ras Protein Signal Transduction Actin Cytoskeleton Organization Regulation Of Establishment Of Cell Polarity Regulation Of Cell Adhesion Regulation Of Cell Motility Regulation Of Establishment Or Maintenance Of Cell Polarity Neuron Projection Morphogenesis Actin Filament-based Process Cellular Protein Modification Process Protein Phosphorylation Regulation Of Epidermal Cell Differentiation Regulation Of Cellular Component Movement Muscle System Process Response To Wounding Regulation Of Focal Adhesion Assembly	Cellular Response To Glucagon Stimulus Response To Glucagon Secretion By Cell Synaptic Transmission Energy Reserve Metabolic Process Secretion Regulation Of Myosin-light-chain-phosphatase Activity Calcium-independent Cell-matrix Adhesion Interleukin-1 Beta Secretion Cellular Response To Acid Chemical Platelet Activation Glutamine Catabolic Process Apolipoprotein A-I-mediated Signaling Pathway Interleukin-1 Secretion Glutamate Biosynthetic Process Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cholesterol Storage High-density Lipoprotein Particle Assembly Muscle Cell Apoptotic Process Establishment Of Localization In Cell Cell-cell Signaling Intracellular Cholesterol Transport Intracellular Sterol Transport Phospholipid Homeostasis Platelet Dense Granule Organization Integrin Activation Phospholipid Efflux Phagocytosis, Engulfment Energy Derivation By Oxidation Of Organic Compounds Regulation Of Respiratory Gaseous Exchange By Neurological System Process Response To Low-density Lipoprotein Particle Interleukin-1 Beta Production Cellular Response To Prostaglandin E Stimulus Cellular Response To Peptide Hormone Stimulus Small Molecule Metabolic Process G-protein Coupled Acetylcholine Receptor Signaling Pathway Cellular Response To Peptide Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Regulation Of Respiratory System Process Cellular Localization G-protein Coupled Receptor Signaling Pathway Cellular Response To Cholesterol Negative Regulation Of Macrophage Derived Foam Cell Differentiation Reverse Cholesterol Transport Response To Laminar Fluid Shear Stress Membrane Invagination Protein-lipid Complex Assembly Response To Lipoprotein Particle Cellular Response To Sterol Positive Regulation Of Cholesterol Efflux
Tagcloud ?			adca adcas arca ascertained ataxia ataxias attct connections cypriot depended drpla encompass geographical hereby pentanucleotide rarer repeat sca sca1 sca10 sca12 sca17 sca2 sca3 sca6 sca7 sca8 scas triplet
Tagcloud (Difference) ?			adca adcas arca ascertained ataxia ataxias attct connections cypriot depended drpla encompass geographical hereby pentanucleotide rarer repeat sca sca1 sca10 sca12 sca17 sca2 sca3 sca6 sca7 sca8 scas triplet
Tagcloud (Intersection) ?