CLUAP1 and UBXN10

Number of citations of the paper that reports this interaction (PubMedID 26389662)
53

Data Source:
BioGRID (pull down)

		CLUAP1	UBXN10
Description		clusterin associated protein 1	UBX domain protein 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Microtubule Organizing Center Cilium Actin Cytoskeleton Intraciliary Transport Particle A Intraciliary Transport Particle B Cell Projection Ciliary Tip Ciliary Base	Endoplasmic Reticulum Cilium Intraciliary Transport Particle B Cell Projection
	Molecular Function	Protein Binding	Protein Binding Ubiquitin Binding
	Biological Process	Neural Tube Closure Heart Looping Smoothened Signaling Pathway Floor Plate Formation Cell Projection Organization Axoneme Assembly Intraciliary Anterograde Transport Cilium Assembly Left/right Pattern Formation	Cell Projection Organization ERAD Pathway Cilium Assembly
Pathways		Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Cerebrospinal fluid α-synuclein levels ( 29959729) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Type 2 diabetes ( 30297969)	Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471)
Interacting Genes		7 interacting genes: APP CINP CLU MAGEA11 MYOG UBXN10 VCP	13 interacting genes: APP CLUAP1 IFT46 IFT57 IFT70A IFT70B IFT80 LRRK2 PRMT6 TRAF3IP1 UBXN6 UNC13A VCP
Entrez ID		23059	127733
HPRD ID		10013	18255
Ensembl ID		ENSG00000103351	ENSG00000162543
Uniprot IDs		J3KNW5 Q96AJ1	Q96LJ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Amyloid Fibril Formation Response To Misfolded Protein Regulation Of Amyloid Fibril Formation Regulation Of Amyloid-beta Clearance Positive Regulation Of Proteolysis Low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Protein Catabolic Process Microglial Cell Activation Positive Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of ATP Metabolic Process Leukocyte Activation Involved In Inflammatory Response Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Receptor-mediated Endocytosis Amyloid-beta Complex Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Response To Calcium Ion Platelet Alpha Granule Lumen Macrophage Activation Amylin Binding Regulation Of Proteolysis Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Catabolic Process Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Nitric Oxide Metabolic Process Perinuclear Endoplasmic Reticulum Lumen Regulation Of Neuronal Signal Transduction Flavin Adenine Dinucleotide Catabolic Process Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Regulation Of Response To Endoplasmic Reticulum Stress Receptor Ligand Activity Lipoprotein Particle Myeloid Leukocyte Activation Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway	Intraciliary Transport Particle B Intraciliary Anterograde Transport Intraciliary Transport Transport Along Microtubule Cytoskeleton-dependent Intracellular Transport Ciliary Tip Microtubule-based Transport Establishment Of Localization In Cell Intracellular Transport Microtubule-based Movement Cellular Localization Microtubule-based Process Cell Projection Cell Projection Organization Cilium Assembly Cilium Organization Ciliary Basal Body Cilium Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Smoothened Signaling Pathway Cellular Component Assembly Plasma Membrane Bounded Cell Projection Organization Intraciliary Transport Particle B Binding Centrosome Ciliary Base Organelle Assembly Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Cellular Response To Manganese Ion Left/right Pattern Formation Response To Manganese Ion Microtubule Organizing Center Golgi-associated Vesicle Regulation Of Wnt Signaling Pathway Cellular Response To Catecholamine Stimulus Syntaxin-1 Binding Response To Catecholamine Negative Regulation Of Keratinocyte Proliferation Regulation Of Proteolysis Organelle Organization Keratinocyte Proliferation Regulation Of Ubiquitin-dependent Protein Catabolic Process Axonemal Microtubule Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of ATP Metabolic Process Anatomical Structure Morphogenesis Terminal Bouton Cytoskeleton Endosome Transport Via Multivesicular Body Sorting Pathway
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