NDUFS7 and ENO2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NDUFS7	ENO2
Gene Name		NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)	enolase 2 (gamma, neuronal)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Neuron Projection Neuronal Cell Body Synaptic Membrane	Phosphopyruvate Hydratase Complex Photoreceptor Inner Segment Extracellular Space Cytosol Plasma Membrane Perikaryon Extracellular Vesicular Exosome
	Molecular Function	Protease Binding NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Metal Ion Binding Quinone Binding 4 Iron, 4 Sulfur Cluster Binding	Magnesium Ion Binding Phosphopyruvate Hydratase Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Respiratory Electron Transport Chain Mitochondrial Respiratory Chain Complex I Assembly Cellular Metabolic Process Small Molecule Metabolic Process	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Small Molecule Metabolic Process
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport	Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs		NADH
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ARRB2 ENO2 ND1	23 interactors: A2M ACD ANXA11 C16orf45 C6orf47 ENSA EXOC5 HABP4 HK1 HSF1 IL17B MAP4 NAT9 NDUFS7 POT1 SIGIRR SNUPN ST3GAL2 SUMO4 TERF1 TINF2 TUBA4A UBE2C
Entrez ID		374291	2026
HPRD ID		03491	00573
Ensembl ID			ENSG00000111674
Uniprot IDs		O75251 Q7LD69	P09104 Q6FHV6
PDB IDs			1TE6 2AKM 2AKZ 3UCC 3UCD 3UJE 3UJF 3UJR 3UJS
Enriched GO Terms of Interacting Partners?		Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Follicle-stimulating Hormone Signaling Pathway Negative Regulation Of Smooth Muscle Cell Apoptotic Process Positive Regulation Of Synaptic Transmission, Dopaminergic Generation Of Precursor Metabolites And Energy Regulation Of Smooth Muscle Cell Apoptotic Process G-protein Coupled Receptor Internalization Negative Regulation Of Interleukin-1 Beta Production Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Synaptic Transmission, Dopaminergic Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Receptor Internalization Positive Regulation Of DNA Biosynthetic Process Negative Regulation Of Interleukin-12 Production Regulation Of Androgen Receptor Signaling Pathway Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Negative Regulation Of Toll-like Receptor Signaling Pathway Detection Of Temperature Stimulus Regulation Of Receptor Internalization Sensory Perception Of Temperature Stimulus Negative Regulation Of Mitochondrion Organization Negative Regulation Of GTPase Activity Negative Regulation Of Muscle Cell Apoptotic Process Negative Regulation Of Interleukin-6 Production Positive Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Innate Immune Response Negative Regulation Of Tumor Necrosis Factor Production Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Receptor Internalization Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of DNA Biosynthetic Process Adult Walking Behavior Regulation Of Interleukin-1 Beta Production Regulation Of Muscle Cell Apoptotic Process Negative Regulation Of Protein Binding Gluconeogenesis Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Mitochondrial ATP Synthesis Coupled Electron Transport Regulation Of Interleukin-12 Production Negative Regulation Of NF-kappaB Transcription Factor Activity Hexose Biosynthetic Process Ovarian Follicle Development	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Replication Regulation Of Telomerase Activity Telomere Maintenance Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Replication Regulation Of DNA Biosynthetic Process Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Mitotic Cell Cycle Process Organelle Organization Cell Division Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Platelet Degranulation Mitotic Cell Cycle Positive Regulation Of Telomere Maintenance Regulation Of Organelle Organization Cell Cycle Positive Regulation Of DNA Biosynthetic Process Cellular Component Assembly G2/M Transition Of Mitotic Cell Cycle RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Exocytosis Cell Cycle Process Positive Regulation Of DNA Metabolic Process Protein Localization To Chromosome Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Organelle Organization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Negative Regulation Of Catalytic Activity Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Platelet Activation Cellular Localization Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Negative Regulation Of Protein ADP-ribosylation
Tagcloud ?		1b accumulate aph causative cleavages compartments earliest fibrous granules gsaps hallmarks intraneuronal knock nadh nicastrin notch polymerization presenilin pyramidal secretase sirnas sulfur synapse synaptic synaptotoxic tppp tubulin ubiquinone vulnerable	begin differentially dige enolase failures gondii gra7 hypothetical imc1 mic2 naturally parasite proteomics pyrimethamine qrt rh rhoptry rop2 rop2a spectrometer spots strains sulfadiazine sulfonamide tga tgh toxoplasma toxoplasmosis undertook
Tagcloud (Difference) ?		1b accumulate aph causative cleavages compartments earliest fibrous granules gsaps hallmarks intraneuronal knock nadh nicastrin notch polymerization presenilin pyramidal secretase sirnas sulfur synapse synaptic synaptotoxic tppp tubulin ubiquinone vulnerable	begin differentially dige enolase failures gondii gra7 hypothetical imc1 mic2 naturally parasite proteomics pyrimethamine qrt rh rhoptry rop2 rop2a spectrometer spots strains sulfadiazine sulfonamide tga tgh toxoplasma toxoplasmosis undertook
Tagcloud (Intersection) ?