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NDUFS7 and ENO2
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
NDUFS7
ENO2
Description
NADH:ubiquinone oxidoreductase core subunit S7
enolase 2
Image
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Matrix
Membrane
Neuronal Cell Body
Respiratory Chain Complex I
Synaptic Membrane
Phosphopyruvate Hydratase Complex
Photoreceptor Inner Segment
Extracellular Space
Cytoplasm
Cytosol
Plasma Membrane
Cell Cortex
Cell Surface
Membrane
Growth Cone
Neuronal Cell Body
Perikaryon
Membrane Raft
Extracellular Exosome
Synaptic Membrane
Molecular Function
Protease Binding
NADH Dehydrogenase Activity
Monooxygenase Activity
Protein Binding
NADH Dehydrogenase (ubiquinone) Activity
Oxidoreductase Activity
Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor
Metal Ion Binding
Quinone Binding
Iron-sulfur Cluster Binding
4 Iron, 4 Sulfur Cluster Binding
Magnesium Ion Binding
Phosphopyruvate Hydratase Activity
Protein Binding
Lyase Activity
Enzyme Binding
Identical Protein Binding
Protein-containing Complex Binding
Metal Ion Binding
Biological Process
Mitochondrial Electron Transport, NADH To Ubiquinone
Aerobic Respiration
Electron Transport Coupled Proton Transport
Mitochondrial Respiratory Chain Complex I Assembly
Proton Motive Force-driven Mitochondrial ATP Synthesis
Gluconeogenesis
Glycolytic Process
Response To Xenobiotic Stimulus
Response To Estradiol
Canonical Glycolysis
Pathways
Respiratory electron transport
Complex I biogenesis
Glycolysis
Gluconeogenesis
Drugs
NADH
2-Phosphoglycolic Acid
Diseases
Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes
3 interacting genes:
ARRB2
ENO2
MT-ND1
27 interacting genes:
A2M
ACD
AKT1
ANXA11
BMERB1
C6orf47
ENSA
EXOC5
HABP4
HK1
HSF1
IL17B
MAP4
MTNR1A
NAT9
NDUFS7
POT1
SIGIRR
SNUPN
ST3GAL2
SUMO4
TERF1
TINF2
TUBA4A
UBE2C
UBE3A
USP2-AS1
Entrez ID
374291
2026
HPRD ID
03491
00573
Ensembl ID
ENSG00000115286
ENSG00000111674
Uniprot IDs
F5H5N1
O75251
Q6ZS38
Q7LD69
P09104
Q6FHV6
PDB IDs
5XTB
5XTD
5XTH
5XTI
1TE6
2AKM
2AKZ
3UCC
3UCD
3UJE
3UJF
3UJR
3UJS
4ZA0
4ZCW
5EU9
5IDZ
5TD9
5TIJ
7MBH
Enriched GO Terms of Interacting Partners
?
Angiotensin Receptor Binding
Positive Regulation Of Synaptic Transmission, Dopaminergic
Regulation Of Synaptic Transmission, Dopaminergic
D1 Dopamine Receptor Binding
Negative Adaptation Of Signaling Pathway
Desensitization Of G Protein-coupled Receptor Signaling Pathway
Beta-arrestin-dependent Dopamine Receptor Signaling Pathway
Response To Xenobiotic Stimulus
Phosphopyruvate Hydratase Complex
Purine Ribonucleotide Metabolic Process
Phosphopyruvate Hydratase Activity
ATP Metabolic Process
Generation Of Precursor Metabolites And Energy
Ribonucleotide Metabolic Process
Ribose Phosphate Metabolic Process
Third Ventricle Development
Positive Regulation Of Cardiac Muscle Cell Differentiation
Protein Kinase B Binding
Purine Nucleotide Metabolic Process
Neuronal Cell Body
NADH Dehydrogenase Activity
Enzyme Binding
G Protein-coupled Receptor Internalization
Nucleotide Metabolic Process
Lateral Ventricle Development
Left/right Pattern Formation
Positive Regulation Of Cardiocyte Differentiation
Shelterin Complex
Nuclear Telomere Cap Complex
Telomere Capping
Telomere Assembly
Negative Regulation Of Telomere Maintenance Via Telomerase
Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Metabolic Process
Positive Regulation Of DNA Metabolic Process
Positive Regulation Of Telomere Maintenance
Telomere Maintenance Via Telomerase
Translation Elongation Factor Binding
Negative Regulation Of Chromosome Organization
RNA-templated DNA Biosynthetic Process
Negative Regulation Of Cellular Component Organization
Regulation Of DNA Biosynthetic Process
Positive Regulation Of Organelle Organization
Telomere Maintenance Via Telomere Lengthening
Telomere Maintenance
Positive Regulation Of Chromosome Organization
Maintenance Of Protein Location In Mitochondrion
Regulation Of Telomere Maintenance
Regulation Of Establishment Of Protein Localization To Telomere
Regulation Of Chromosome Organization
Regulation Of Establishment Of Protein Localization To Chromosome
Telomere Organization
Telomerase Inhibitor Activity
Establishment Of Protein Localization To Telomere
Regulation Of Organelle Organization
Telomeric D-loop Disassembly
G-rich Strand Telomeric DNA Binding
Regulation Of DNA Metabolic Process
Telomeric Loop Disassembly
Protein Localization To Chromosome, Telomeric Region
Chromosome, Telomeric Region
Establishment Of Protein Localization To Organelle
Organelle Organization
DNA Biosynthetic Process
Anaphase-promoting Complex-dependent Catabolic Process
Negative Regulation Of Cilium Assembly
Cell Division
Microtubule Cytoskeleton
Ubiquitin-like Protein Ligase Binding
Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Positive Regulation Of Mitotic Cell Cycle
Regulation Of TRNA Methylation
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