NDUFS7 and ND1

Number of citations of the paper that reports this interaction (PMID 11418099)
18

Data Source:
HPRD (in vitro)

		NDUFS7	ND1
Gene Name		NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)	NADH dehydrogenase, subunit 1 (complex I)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Neuron Projection Neuronal Cell Body Synaptic Membrane
	Molecular Function	Protease Binding NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Metal Ion Binding Quinone Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Respiratory Electron Transport Chain Mitochondrial Respiratory Chain Complex I Assembly Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs		NADH
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ARRB2 ENO2 ND1	10 interactors: BARD1 BRCA1 DHDDS LIG4 MEOX2 NDUFS7 PAXIP1 RPL13A RPL6 TST
Entrez ID		374291	4535
HPRD ID		03491	08365
Ensembl ID
Uniprot IDs		O75251 Q7LD69	P03886 Q85KV6
PDB IDs
Enriched GO Terms of Interacting Partners?		Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Follicle-stimulating Hormone Signaling Pathway Negative Regulation Of Smooth Muscle Cell Apoptotic Process Positive Regulation Of Synaptic Transmission, Dopaminergic Generation Of Precursor Metabolites And Energy Regulation Of Smooth Muscle Cell Apoptotic Process G-protein Coupled Receptor Internalization Negative Regulation Of Interleukin-1 Beta Production Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Synaptic Transmission, Dopaminergic Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Receptor Internalization Positive Regulation Of DNA Biosynthetic Process Negative Regulation Of Interleukin-12 Production Regulation Of Androgen Receptor Signaling Pathway Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Negative Regulation Of Toll-like Receptor Signaling Pathway Detection Of Temperature Stimulus Regulation Of Receptor Internalization Sensory Perception Of Temperature Stimulus Negative Regulation Of Mitochondrion Organization Negative Regulation Of GTPase Activity Negative Regulation Of Muscle Cell Apoptotic Process Negative Regulation Of Interleukin-6 Production Positive Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Innate Immune Response Negative Regulation Of Tumor Necrosis Factor Production Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Receptor Internalization Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of DNA Biosynthetic Process Adult Walking Behavior Regulation Of Interleukin-1 Beta Production Regulation Of Muscle Cell Apoptotic Process Negative Regulation Of Protein Binding Gluconeogenesis Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Mitochondrial ATP Synthesis Coupled Electron Transport Regulation Of Interleukin-12 Production Negative Regulation Of NF-kappaB Transcription Factor Activity Hexose Biosynthetic Process Ovarian Follicle Development	Protein K6-linked Ubiquitination Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Histone H3-K4 Methylation Nitrogen Compound Metabolic Process Positive Regulation Of Histone Acetylation Response To Ionizing Radiation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Nucleobase-containing Compound Metabolic Process DNA Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Histone Methylation DNA Recombination Cellular Macromolecule Biosynthetic Process Regulation Of Histone Acetylation Macromolecule Biosynthetic Process Regulation Of Histone Methylation Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Neuron Death Positive Regulation Of Histone Modification Positive Regulation Of Histone H4-K20 Methylation Negative Regulation Of Formation Of Translation Preinitiation Complex Positive Regulation Of Histone H3-K36 Methylation DNA Ligation Involved In DNA Recombination Positive Regulation Of Histone H4-K16 Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Viral Transcription DNA Metabolic Process Signal Transduction In Response To DNA Damage Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Response To Radiation Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of MRNA 3'-end Processing Cyanate Catabolic Process Biosynthetic Process Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Protein Localization To Endoplasmic Reticulum Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation RNA Import Into Mitochondrion RRNA Import Into Mitochondrion Viral Process
Tagcloud ?		1b accumulate aph causative cleavages compartments earliest fibrous granules gsaps hallmarks intraneuronal knock nadh nicastrin notch polymerization presenilin pyramidal secretase sirnas sulfur synapse synaptic synaptotoxic tppp tubulin ubiquinone vulnerable	12s 16s 18s coi cys distinction eastern genus honshu japan markers mature met mitochondrial mountainous oka orobdella orobdellamasaakikuroiwai orobdellawhitmani phylogenetic phylogroups quadrannulate rdna relationships reveled sister sp trna val
Tagcloud (Difference) ?		1b accumulate aph causative cleavages compartments earliest fibrous granules gsaps hallmarks intraneuronal knock nadh nicastrin notch polymerization presenilin pyramidal secretase sirnas sulfur synapse synaptic synaptotoxic tppp tubulin ubiquinone vulnerable	12s 16s 18s coi cys distinction eastern genus honshu japan markers mature met mitochondrial mountainous oka orobdella orobdellamasaakikuroiwai orobdellawhitmani phylogenetic phylogroups quadrannulate rdna relationships reveled sister sp trna val
Tagcloud (Intersection) ?