MAP1LC3C and RESF1

Number of citations of the paper that reports this interaction (PubMedID 37219487)
66

Data Source:
BioGRID (unspecified method)

		MAP1LC3C	RESF1
Description		microtubule associated protein 1 light chain 3 gamma	retroelement silencing factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Cytoplasm Autophagosome Cytosol Cytoskeleton Microtubule Endomembrane System Membrane Organelle Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule	Nucleus
	Molecular Function	Protein Binding Phospholipid Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding	Protein Binding Histone Binding Histone Methyltransferase Binding
	Biological Process	Autophagosome Assembly Mitophagy Autophagy Response To Stress Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Protein Exit From Endoplasmic Reticulum Aggrephagy Autophagosome Maturation	Transposable Element Silencing By Heterochromatin Formation
Pathways		Macroautophagy
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 28552196) Metabolite levels ( 23823483)
Interacting Genes		41 interacting genes: AMBRA1 ANK2 ANK3 APPL1 ATG13 ATXN3 BICC1 CALCOCO2 CAPN3 CDC37 CUL3 GMEB2 IRGM KBTBD6 KBTBD7 LAT LMNB1 MEFV MISP NCOR1 NEDD4 NIPBL OPRM1 OPTN PDLIM1 RESF1 RHOXF1 RUFY4 SAMM50 STK3 TAX1BP1 TBC1D25 TNIP1 TP53INP1 TRIM21 TRIM25 TRIM32 TSR2 WDFY3 WDR81 ZNF24	10 interacting genes: EXOC1 GABARAP GABARAPL1 GABARAPL2 KRT36 KRT86 MAP1LC3A MAP1LC3C MDM2 TBC1D4
Entrez ID		440738	55196
HPRD ID		14226	07691
Ensembl ID		ENSG00000197769	ENSG00000174718
Uniprot IDs		Q9BXW4	Q9HCM1
PDB IDs		2NCN 3VVW 3WAM 3WAP 5DPW
Enriched GO Terms of Interacting Partners?		Autophagosome Positive Regulation Of Autophagy Regulation Of Autophagy Autophagy Positive Regulation Of Catabolic Process Regulation Of Macroautophagy Catabolic Process Autophagosome Assembly Positive Regulation Of Macroautophagy Autophagosome Organization Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Protein Polyubiquitination Vacuole Organization Protein K48-linked Ubiquitination Regulation Of Intracellular Signal Transduction Cytosol Organelle Organization Regulation Of Cell Communication Cytoplasmic Vesicle Regulation Of Innate Immune Response Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Signal Transduction Protein Localization To Organelle Macroautophagy Regulation Of Protein Stability Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Signal Transduction Post-translational Protein Modification Proteolysis Involved In Protein Catabolic Process Macromolecule Catabolic Process Innate Immune Response-activating Signaling Pathway Organelle Assembly Ubiquitin-dependent Protein Catabolic Process Protein Localization To Phagocytic Vesicle Regulation Of Autophagosome Maturation Modification-dependent Protein Catabolic Process Cytoplasm Regulation Of Gene Expression Intracellular Protein Localization Regulation Of Macromolecule Metabolic Process Suppression Of Viral Release By Host Autophagosome Membrane Regulation Of Signaling Activation Of Innate Immune Response Protein Monoubiquitination Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Macromolecule Biosynthetic Process Protein-macromolecule Adaptor Activity	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome Autophagosome Assembly Autophagosome Organization Cellular Response To Nutrient Levels Phospholipid Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Disassembly Macroautophagy Vacuole Organization Cellular Response To Starvation Response To Starvation Response To Nutrient Levels GABA Receptor Binding Autophagy Beta-tubulin Binding Cytosol Organelle Assembly Microtubule Protein-containing Complex Organization Cytoplasmic Vesicle Cellular Response To Stress Organelle Organization Response To Iron Ion Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Organelle Membrane Microtubule Binding Endomembrane System Establishment Of Protein Localization Response To Stress Structural Constituent Of Skin Epidermis Response To Formaldehyde Cellular Response To Vitamin B1 Cellular Response To Hydrogen Peroxide Cytoskeleton Intermediate Filament Organization Cellular Component Assembly Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Proteolysis Keratin Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Response To Hydrogen Peroxide
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