RESF1 and KRT86

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RESF1	KRT86
Description		retroelement silencing factor 1	keratin 86
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Space Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding Histone Binding Histone Methyltransferase Binding	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Transposable Element Silencing By Heterochromatin Formation	Keratinization Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases			Monilethrix
GWAS			Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715) Diisocyanate-induced asthma ( 25918132) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes		10 interacting genes: EXOC1 GABARAP GABARAPL1 GABARAPL2 KRT36 KRT86 MAP1LC3A MAP1LC3C MDM2 TBC1D4	45 interacting genes: CAMK2B CCDC146 CDK18 CEP57 CREB5 CYSRT1 GNE HGS HSD3B7 IL16 JOSD1 KANK2 KRT14 KRT15 KRT16 KRT19 KRT25 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT76 MAPKBP1 MEOX2 MGAT5B MKRN3 NUTF2 ODF1 OIP5 OLIG3 RESF1 RTP5 SHC3 TEKT4 TSGA10IP ZNF414 ZNF655
Entrez ID		55196	3892
HPRD ID		07691	03567
Ensembl ID		ENSG00000174718	ENSG00000170442
Uniprot IDs		Q9HCM1	A8K872 O43790
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Of Mitochondrion Autophagosome Autophagosome Assembly Autophagosome Organization Cellular Response To Nutrient Levels Phospholipid Binding Ubiquitin Protein Ligase Binding Protein-containing Complex Disassembly Macroautophagy Vacuole Organization Cellular Response To Starvation Response To Starvation Response To Nutrient Levels GABA Receptor Binding Autophagy Beta-tubulin Binding Cytosol Organelle Assembly Microtubule Protein-containing Complex Organization Cytoplasmic Vesicle Cellular Response To Stress Organelle Organization Response To Iron Ion Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Organelle Membrane Microtubule Binding Endomembrane System Establishment Of Protein Localization Response To Stress Structural Constituent Of Skin Epidermis Response To Formaldehyde Cellular Response To Vitamin B1 Cellular Response To Hydrogen Peroxide Cytoskeleton Intermediate Filament Organization Cellular Component Assembly Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Proteolysis Keratin Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Response To Hydrogen Peroxide	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Cytoskeleton Cytoskeleton Organization Epidermis Development Anatomical Structure Morphogenesis Hair Cycle Organelle Organization Cell Differentiation Extracellular Exosome Cellular Developmental Process Structural Constituent Of Cytoskeleton Tissue Development Protein Binding Developmental Process Hair Follicle Morphogenesis Cytosol Cornified Envelope Hair Cycle Process
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