RNASEK and TMEM203

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RNASEK	TMEM203
Description		ribonuclease K	transmembrane protein 203
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Plasma Membrane Endosome Membrane Endomembrane System Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex	Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Hydrolase Activity	Protein Binding
	Biological Process	Monoatomic Ion Transport Endocytosis Receptor-mediated Endocytosis Vacuolar Acidification Lysosomal Lumen Acidification Receptor-mediated Endocytosis Of Virus By Host Cell Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Proton Transmembrane Transport	Intracellular Calcium Ion Homeostasis Spermatogenesis
Pathways
Drugs
Diseases
GWAS
Interacting Genes		26 interacting genes: ARV1 ATP13A1 BNIP3 CYSLTR2 FIS1 FXYD6 GIMAP5 HMOX2 LRCH4 NINJ2 RTP2 SEC22A SERF1A SERF1B SERP2 SMAGP STX8 TAAR1 TIMM23 TMEM203 TMEM222 TMEM60 TREX1 VAPB VTI1B ZDHHC21	41 interacting genes: ANK1 AQP6 ATP6AP2 CD3G CNR2 CPLX4 CREB3 CREB3L1 EBP ELOVL4 ERGIC3 FAM174A FAM209A FFAR2 GPX8 HSD17B11 HSD17B13 KCNJ6 LMNA LY6G6C MANBAL MMD PDZK1IP1 RETREG3 RMDN3 RNASEK SCN3B SLC10A6 SLC18A1 SLC61A1 SSMEM1 STOM STX4 TIMMDC1 TMEM14B TMEM234 TMEM31 TMEM52B TMEM60 TMEM86B TMX2
Entrez ID		440400	94107
HPRD ID		17568	17496
Ensembl ID		ENSG00000219200	ENSG00000187713
Uniprot IDs		A0A0C4DH89 Q6P5S7	Q969S6
PDB IDs		6WLW 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Membrane Organization Chloride Channel Inhibitor Activity Establishment Of Protein Localization Mitochondrial Fragmentation Involved In Apoptotic Process Intracellular Calcium Ion Homeostasis Cellular Localization Organelle Localization By Membrane Tethering Protein Targeting Calcium Ion Homeostasis Membrane Docking Positive Regulation Of Mitochondrial Fission Intracellular Chemical Homeostasis Regulation Of Mitochondrial Fission Mitochondrion Autophagosome Adaptor Activity Amyloid Fibril Formation Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Protein Targeting To Mitochondrion Cysteinyl Leukotriene Receptor Activity Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity Regulation Of Plasma Membrane Sterol Distribution G Protein-coupled Amine Receptor Activity Membrane Fusion Macroautophagy	Membrane Endoplasmic Reticulum Steroid Dehydrogenase Activity Protein Binding Endoplasmic Reticulum Membrane Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V0 Domain
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