RNASEK and ARV1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RNASEK	ARV1
Description		ribonuclease K	ARV1 fatty acid homeostasis modulator
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Plasma Membrane Endosome Membrane Endomembrane System Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Cortical Endoplasmic Reticulum
	Molecular Function	Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Hydrolase Activity	Protein Binding Sterol Transfer Activity
	Biological Process	Monoatomic Ion Transport Endocytosis Receptor-mediated Endocytosis Vacuolar Acidification Lysosomal Lumen Acidification Receptor-mediated Endocytosis Of Virus By Host Cell Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Proton Transmembrane Transport	Lipid Metabolic Process Sphingolipid Metabolic Process Cholesterol Biosynthetic Process Lipid Transport Steroid Metabolic Process Cholesterol Metabolic Process Bile Acid Metabolic Process Sterol Metabolic Process Cholesterol Transport Intracellular Sterol Transport Regulation Of Intracellular Cholesterol Transport Regulation Of Cholesterol Metabolic Process Regulation Of Plasma Membrane Sterol Distribution
Pathways			Cholesterol biosynthesis
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		26 interacting genes: ARV1 ATP13A1 BNIP3 CYSLTR2 FIS1 FXYD6 GIMAP5 HMOX2 LRCH4 NINJ2 RTP2 SEC22A SERF1A SERF1B SERP2 SMAGP STX8 TAAR1 TIMM23 TMEM203 TMEM222 TMEM60 TREX1 VAPB VTI1B ZDHHC21	15 interacting genes: ADRB2 AQP6 CREB3L1 EBP FAM209A GPR152 MUC1 RNASEK SCN3B SLC10A6 SMO TLCD4 TMEM14B TMEM31 TMX2
Entrez ID		440400	64801
HPRD ID		17568	12494
Ensembl ID		ENSG00000219200	ENSG00000173409
Uniprot IDs		A0A0C4DH89 Q6P5S7	Q9H2C2
PDB IDs		6WLW 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Membrane Organization Chloride Channel Inhibitor Activity Establishment Of Protein Localization Mitochondrial Fragmentation Involved In Apoptotic Process Intracellular Calcium Ion Homeostasis Cellular Localization Organelle Localization By Membrane Tethering Protein Targeting Calcium Ion Homeostasis Membrane Docking Positive Regulation Of Mitochondrial Fission Intracellular Chemical Homeostasis Regulation Of Mitochondrial Fission Mitochondrion Autophagosome Adaptor Activity Amyloid Fibril Formation Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Protein Targeting To Mitochondrion Cysteinyl Leukotriene Receptor Activity Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity Regulation Of Plasma Membrane Sterol Distribution G Protein-coupled Amine Receptor Activity Membrane Fusion Macroautophagy	Membrane
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