RNASEK and TAAR1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		RNASEK	TAAR1
Description		ribonuclease K	trace amine associated receptor 1
Image
GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Plasma Membrane Endosome Membrane Endomembrane System Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Endomembrane System Membrane
	Molecular Function	Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Hydrolase Activity	Trace-amine Receptor Activity G Protein-coupled Receptor Activity G Protein-coupled Amine Receptor Activity
	Biological Process	Monoatomic Ion Transport Endocytosis Receptor-mediated Endocytosis Vacuolar Acidification Lysosomal Lumen Acidification Receptor-mediated Endocytosis Of Virus By Host Cell Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Proton Transmembrane Transport	Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Pathways			Amine ligand-binding receptors G alpha (s) signalling events
Drugs			Amphetamine Lisdexamfetamine Dextroamphetamine Metamfetamine Propylhexedrine SEP-363856
Diseases
GWAS			Compulsion score in obsessive compulsive disorder ( 32063569)
Interacting Genes		26 interacting genes: ARV1 ATP13A1 BNIP3 CYSLTR2 FIS1 FXYD6 GIMAP5 HMOX2 LRCH4 NINJ2 RTP2 SEC22A SERF1A SERF1B SERP2 SMAGP STX8 TAAR1 TIMM23 TMEM203 TMEM222 TMEM60 TREX1 VAPB VTI1B ZDHHC21	4 interacting genes: GRIK1 PCMT1 RNASEK SVOP
Entrez ID		440400	134864
HPRD ID		17568	18142
Ensembl ID		ENSG00000219200	ENSG00000146399
Uniprot IDs		A0A0C4DH89 Q6P5S7	Q96RJ0
PDB IDs		6WLW 6WM2 6WM3 6WM4 7U4T 7UNF	8JLN 8JLO 8JLP 8JLQ 8JLR 8JSO 8UHB 8W87 8W88 8W89 8W8A 8WC8 8WCA 8ZSJ 8ZSP 8ZSS 9JKQ
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity Membrane Organization Chloride Channel Inhibitor Activity Establishment Of Protein Localization Mitochondrial Fragmentation Involved In Apoptotic Process Intracellular Calcium Ion Homeostasis Cellular Localization Organelle Localization By Membrane Tethering Protein Targeting Calcium Ion Homeostasis Membrane Docking Positive Regulation Of Mitochondrial Fission Intracellular Chemical Homeostasis Regulation Of Mitochondrial Fission Mitochondrion Autophagosome Adaptor Activity Amyloid Fibril Formation Immune Complex Formation Adenyl Deoxyribonucleotide Binding Immune Response In Brain Or Nervous System Protein Targeting To Mitochondrion Cysteinyl Leukotriene Receptor Activity Extraction Of Mislocalized Protein From ER Membrane ABC-type Manganese Transporter Activity Membrane Protein Dislocase Activity Regulation Of Plasma Membrane Sterol Distribution G Protein-coupled Amine Receptor Activity Membrane Fusion Macroautophagy	Glutamate-gated Calcium Ion Channel Activity Glutamate-gated Receptor Activity Kainate Selective Glutamate Receptor Complex Transmembrane Transport Kainate Selective Glutamate Receptor Activity Protein-L-isoaspartate (D-aspartate) O-methyltransferase Activity Protein Repair Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V0 Domain Endosomal Lumen Acidification Endocytosis Involved In Viral Entry Into Host Cell Receptor-mediated Endocytosis Of Virus By Host Cell Proton-transporting V-type ATPase Complex Ionotropic Glutamate Receptor Signaling Pathway Ligand-gated Monoatomic Ion Channel Activity Protein Methylation Lysosomal Lumen Acidification Clathrin-coated Vesicle Membrane RNA Endonuclease Activity Regulation Of Lysosomal Lumen PH Vacuolar Acidification Synaptic Transmission, Glutamatergic Ligand-gated Ion Channel Signaling Pathway Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential Xenobiotic Transport
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