TMEM203 and PDZK1IP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM203	PDZK1IP1
Description		transmembrane protein 203	PDZK1 interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Plasma Membrane Membrane Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Spermatogenesis
Pathways
Drugs
Diseases
GWAS			Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		41 interacting genes: ANK1 AQP6 ATP6AP2 CD3G CNR2 CPLX4 CREB3 CREB3L1 EBP ELOVL4 ERGIC3 FAM174A FAM209A FFAR2 GPX8 HSD17B11 HSD17B13 KCNJ6 LMNA LY6G6C MANBAL MMD PDZK1IP1 RETREG3 RMDN3 RNASEK SCN3B SLC10A6 SLC18A1 SLC61A1 SSMEM1 STOM STX4 TIMMDC1 TMEM14B TMEM234 TMEM31 TMEM52B TMEM60 TMEM86B TMX2	77 interacting genes: AGR3 AIG1 APOA2 APOD AQP2 AQP6 ARL13B ASGR1 C14orf180 C2CD2L CD81 CES1 CLDN19 COPS6 CYB5B CYBC1 EMC6 ERG28 FAM3C FCER1G GALNT15 GAST GIMAP5 GRM2 GYPA HMOX1 ICMT IGFBP5 JAGN1 LEPROTL1 LHFPL5 MIP MYADM MYADML2 NSG1 NUMB PDZK1 PEX16 PGAP2 PLP2 PLPP4 PLPP6 PMP22 RPRM RTP2 SDCBP SFTPC SFXN2 SLC22A1 SLC22A2 SLC35B1 SLC35B4 STRIT1 STX12 THBD TMEM101 TMEM107 TMEM109 TMEM11 TMEM140 TMEM14A TMEM14B TMEM14C TMEM203 TMEM39B TMEM65 TMEM86A TMEM97 TNFRSF10C TRARG1 TRIM54 TSPO2 UPK1B UTP14A VAMP3 YIPF6 ZDHHC17
Entrez ID		94107	10158
HPRD ID		17496	06211
Ensembl ID		ENSG00000187713	ENSG00000162366
Uniprot IDs		Q969S6	Q13113
PDB IDs			7VSI 7WMV 7YNI 7YNJ 7YNK 8HB0 8HDH 8HEZ 8HG7 8HIN
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Steroid Dehydrogenase Activity Protein Binding Endoplasmic Reticulum Membrane Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V0 Domain	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Localization Within Membrane Organic Hydroxy Compound Transport Protein Binding Cholesterol Binding Establishment Of Protein Localization To Membrane Protein Localization To Cell Periphery Protein Localization To Membrane Serotonin Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Cellular Response To Lipoprotein Particle Stimulus Quaternary Ammonium Group Transport Water Channel Activity Cellular Localization Organic Cation Transport Putrescine Transmembrane Transporter Activity Lipid Transport Acetylcholine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Transmembrane Transport Water Transport Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Protein Localization To Plasma Membrane Cholesterol Transport Monoamine Transport Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Cellular Response To Low-density Lipoprotein Particle Stimulus Carnitine Transmembrane Transport Carnitine Transport Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Sterol Transport Regulation Of Transport Renal Water Transport Fluid Transport Heme Metabolic Process Serotonin Uptake Norepinephrine Transport Neutrophil Differentiation
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