KRTAP5-11 and NECTIN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP5-11	NECTIN3
Description		keratin associated protein 5-11	nectin cell adhesion molecule 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Plasma Membrane Cell-cell Junction Adherens Junction Membrane Axon Dendrite Apical Junction Complex Cell-cell Contact Zone Synapse Postsynaptic Membrane Anchoring Junction Hippocampal Mossy Fiber To CA3 Synapse Postsynaptic Density Membrane
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding Cell Adhesion Mediator Activity
	Biological Process		Lens Morphogenesis In Camera-type Eye Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Fertilization Symbiont Entry Into Host Cell Retina Morphogenesis In Camera-type Eye Establishment Of Protein Localization To Plasma Membrane Cochlea Morphogenesis Cell-cell Adhesion Regulation Of Postsynapse Assembly Protein Localization To Cell Junction
Pathways		Keratinization	Adherens junctions interactions Nectin/Necl trans heterodimerization
Drugs
Diseases
GWAS			Feeling hurt ( 29500382)
Interacting Genes		65 interacting genes: CATSPER1 CRCT1 CREB5 CYSRT1 FAM76B GLRX3 GORASP2 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NECTIN3 NOTCH2NLA NR4A3 NUFIP2 OTX1 POU4F2 RGS17 RGS20 SH3GLB2 SMCP SPRY4 TMEM190 TRIM42 VASN VGLL3	24 interacting genes: AFDN CYSRT1 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-1 KRTAP4-11 KRTAP4-2 KRTAP5-11 KRTAP5-9 KRTAP9-3 NBPF19 NECTIN1 NECTIN2 NOTCH2NLA OTX1 PARD3 PICK1 PVR RGS20 TIGIT
Entrez ID		440051	25945
HPRD ID		17248	08454
Ensembl ID		ENSG00000204571	ENSG00000177707
Uniprot IDs		Q6L8G4	Q9NQS3
PDB IDs			4FOM
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Identical Protein Binding Protein Binding	Intermediate Filament Keratin Filament Susceptibility To T Cell Mediated Cytotoxicity Cell-cell Contact Zone Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Cell Adhesion Molecule Binding Apical Junction Complex Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Identical Protein Binding Cell Adhesion Mediator Activity Adherens Junction Leukocyte Mediated Cytotoxicity Hair Cycle Virus Receptor Activity Positive Regulation Of Immune Response To Tumor Cell Negative Regulation Of Innate Immune Response Regulation Of Leukocyte Mediated Cytotoxicity Symbiont Entry Into Host Cell Lymphocyte Mediated Immunity Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cytosol Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Response To Tumor Cell Positive Regulation Of T Cell Mediated Cytotoxicity Leukocyte Mediated Immunity Positive Regulation Of Natural Killer Cell Mediated Immunity Tight Junction Diencephalon Morphogenesis Coreceptor-mediated Virion Attachment To Host Cell Cellular Anatomical Entity Morphogenesis Biological Process Involved In Interaction With Host Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Bicellular Tight Junction Assembly Regulation Of T Cell Mediated Cytotoxicity Cell-cell Junction Organization Cell Killing Tight Junction Assembly Tight Junction Organization Regulation Of Lymphocyte Mediated Immunity Sperm Mitochondrion Organization BBSome Binding Cell-cell Junction Coreceptor Activity Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
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