MPL and ATXN2L

Number of citations of the paper that reports this interaction (PMID 11784712)
2

Data Source:
HPRD (in vivo)

		MPL	ATXN2L
Gene Name		MPL proto-oncogene, thrombopoietin receptor	ataxin 2-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm Cytoplasmic Stress Granule Membrane Nuclear Speck
	Molecular Function	Transmembrane Signaling Receptor Activity Cytokine Receptor Activity	Protein Binding Poly(A) RNA Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Blood Coagulation Cell Proliferation Cytokine-mediated Signaling Pathway Platelet Activation Regulation Of Chemokine Production Homeostasis Of Number Of Cells	Regulation Of Cytoplasmic MRNA Processing Body Assembly Stress Granule Assembly
Pathways		Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation)
Drugs
Diseases
GWAS			Body mass index ( 20935630) Educational attainment ( 23722424)
Protein-Protein Interactions		9 interactors: ANKRA2 ATXN2L IRS2 JAK2 PTPN11 SHC1 SOCS1 THPO YWHAQ	4 interactors: ATXN1 EPOR HADHA MPL
Entrez ID		4352	11273
HPRD ID		01161	06394
Ensembl ID		ENSG00000117400	ENSG00000168488
Uniprot IDs		P40238	H3BUF6 Q8WWM7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Peptide Hormone Stimulus Regulation Of Interferon-gamma-mediated Signaling Pathway Cellular Response To Peptide JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Response To Interferon-gamma Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Growth Hormone Response To Peptide JAK-STAT Cascade Cellular Response To Hormone Stimulus Regulation Of Immune System Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Regulation Of Kinase Activity Innate Immune Response Regulation Of Cytokine-mediated Signaling Pathway Response To Organonitrogen Compound Positive Regulation Of Hormone Secretion Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Response To Hormone Interferon-gamma-mediated Signaling Pathway Blood Coagulation Hemostasis Positive Regulation Of MAPK Cascade Cytokine-mediated Signaling Pathway Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Signaling Cellular Response To Interferon-gamma Regulation Of Protein Phosphorylation Insulin Receptor Signaling Pathway Regulation Of Cellular Ketone Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Response To Interferon-gamma Negative Regulation Of Lipid Transport Immune System Process Regulation Of Body Fluid Levels Cellular Response To Fibroblast Growth Factor Stimulus Cellular Response To Cytokine Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Signal Transduction Wound Healing Regulation Of Insulin Secretion	Erythropoietin-mediated Signaling Pathway Cellular Response To Erythropoietin Cardiolipin Acyl-chain Remodeling Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Tagcloud ?		advances begun biology commitment correlate determination developmental dlk experimental flk gata genetic hematopoietic hoxb4 identify impact implicated loci major mapping numbers others recently regulators scl stem strategies strongly variety
Tagcloud (Difference) ?		advances begun biology commitment correlate determination developmental dlk experimental flk gata genetic hematopoietic hoxb4 identify impact implicated loci major mapping numbers others recently regulators scl stem strategies strongly variety
Tagcloud (Intersection) ?