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MPL
Gene Name
MPL proto-oncogene, thrombopoietin receptor
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Molecular Function
Transmembrane Signaling Receptor Activity
Cytokine Receptor Activity
Biological Process
Cell Surface Receptor Signaling Pathway
Blood Coagulation
Cell Proliferation
Cytokine-mediated Signaling Pathway
Platelet Activation
Regulation Of Chemokine Production
Homeostasis Of Number Of Cells
Pathways
Platelet activation, signaling and aggregation
Platelet Aggregation (Plug Formation)
Drugs
Diseases
GWAS
Protein-protein Interactions
9 interactors:
ANKRA2
ATXN2L
IRS2
JAK2
PTPN11
SHC1
SOCS1
THPO
YWHAQ
Entrez ID
4352
HPRD ID
01161
Ensembl ID
ENSG00000117400
Uniprot IDs
P40238
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cellular Response To Peptide Hormone Stimulus
Regulation Of Interferon-gamma-mediated Signaling Pathway
Cellular Response To Peptide
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Regulation Of Response To Interferon-gamma
Growth Hormone Receptor Signaling Pathway
Cellular Response To Growth Hormone Stimulus
Response To Peptide Hormone
Cellular Response To Organonitrogen Compound
Response To Growth Hormone
Response To Peptide
JAK-STAT Cascade
Cellular Response To Hormone Stimulus
Regulation Of Immune System Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Phosphorylation
Regulation Of Phosphorus Metabolic Process
Regulation Of Kinase Activity
Innate Immune Response
Regulation Of Cytokine-mediated Signaling Pathway
Response To Organonitrogen Compound
Positive Regulation Of Hormone Secretion
Regulation Of Immune Response
Enzyme Linked Receptor Protein Signaling Pathway
Response To Hormone
Interferon-gamma-mediated Signaling Pathway
Blood Coagulation
Hemostasis
Positive Regulation Of MAPK Cascade
Cytokine-mediated Signaling Pathway
Intracellular Signal Transduction
Cellular Response To Organic Substance
Regulation Of Signaling
Cellular Response To Interferon-gamma
Regulation Of Protein Phosphorylation
Insulin Receptor Signaling Pathway
Regulation Of Cellular Ketone Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Response To Interferon-gamma
Negative Regulation Of Lipid Transport
Immune System Process
Regulation Of Body Fluid Levels
Cellular Response To Fibroblast Growth Factor Stimulus
Cellular Response To Cytokine Stimulus
Response To Fibroblast Growth Factor
Positive Regulation Of Signal Transduction
Wound Healing
Regulation Of Insulin Secretion
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