CD99 and FTH1

Number of citations of the paper that reports this interaction (PubMedID 15388255)
0

Data Source:
HPRD (two hybrid)

		CD99	FTH1
Description		CD99 molecule (Xg blood group)	ferritin heavy chain 1
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Focal Adhesion Membrane	Extracellular Region Nucleus Cytoplasm Lysosome Autophagosome Cytosol Cytoplasmic Vesicle Autolysosome Extracellular Exosome Ferritin Complex Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding	Ferroxidase Activity Iron Ion Binding Protein Binding Ferrous Iron Binding Ferric Iron Binding Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Iron Ion Sequestering Activity
	Biological Process	Cell Adhesion Homotypic Cell-cell Adhesion T Cell Extravasation Positive Regulation Of Neutrophil Extravasation	Iron Ion Transport Intracellular Iron Ion Homeostasis Immune Response Negative Regulation Of Cell Population Proliferation Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Ferroptosis
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall	Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport
Drugs			Iron Dextran Iron Ferric pyrophosphate citrate Ferrous gluconate Ferrous succinate Ferrous ascorbate Ferrous fumarate Ferrous glycine sulfate
Diseases
GWAS			Estradiol levels ( 22675492) Major depressive disorder x sex interaction ( 34099189) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)
Interacting Genes		12 interacting genes: ANXA2 ENTR1 FTH1 KPNB1 MTNR1A MTNR1B PPIA SGTA TRIP13 UBE2H UBQLN1 UBQLN4	42 interacting genes: BAG4 BRD7 CD99 CDC16 CDC25A CDC42 CRMP1 CSF3R CSNK2B DAXX DLG4 ELL3 FTL FXR1 FXR2 GOLM1 GPR35 GRB2 KPNA2 LBP MAX MYL3 NR1I3 NR3C1 NR5A2 NTAQ1 OPTN PACSIN1 PCBP1 PCBP2 PIAS4 SDCBP SIRPA SNCA SOX5 SPP1 STAT1 TICAM2 TOLLIP TRAF4 UBR1 YWHAE
Entrez ID		4267	2495
HPRD ID		02434	00615
Ensembl ID		ENSG00000002586	ENSG00000167996
Uniprot IDs		A0A096LP69 P14209	P02794
PDB IDs		7SFX	1FHA 2CEI 2CHI 2CIH 2CLU 2CN6 2CN7 2FHA 2IU2 2Z6M 3AJO 3AJP 3AJQ 3ERZ 3ES3 4DYX 4DYY 4DYZ 4DZ0 4OYN 4Y08 4YKH 4ZJK 5CMQ 5CMR 5GN8 5GOU 5JKK 5JKL 5JKM 5N26 5N27 5UP7 5UP8 5UP9 5VTD 5XB1 5YI5 5ZND 6B8F 6B8G 6FTV 6GSR 6H5I 6H6T 6H6U 6IPC 6IPO 6IPP 6IPQ 6J4A 6J7G 6JOB 6JPS 6KE2 6KE4 6M52 6M54 6WYF 6WYG 6WYH 6Z6U 6Z9E 6Z9F 7A6A 7A6B 7CK8 7CK9 7JGK 7JGL 7JGM 7JGN 7JGO 7JGP 7JGQ 7K26 7K3V 7K3W 7KE3 7KE5 7PF1 7R5O 7RRP 7V66 7VD8 7ZG7 8A2L 8A2M 8A5N 8AAV 8B7O 8CPM 8CPS 8CPT 8CPU 8CPV 8CPW 8CPX 8DHX 8DNP 8F49 8F4L 8HHS 8J9L 8J9M 8JAI 8KFD 8PP2 8PP3 8PP5 8QU9 8W92 8WB3 8WIE 8WIQ 8WJF 8XWB 8Y6F 9JIU 9JQB 9JQC 9JQD 9JQE 9KAY
Enriched GO Terms of Interacting Partners?		Melatonin Receptor Activity Autophagosome Regulation Of Protein Catabolic Process Regulation Of Proteolysis Ficolin-1-rich Granule Lumen Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Proteolysis Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Proteasomal Protein Catabolic Process Polyubiquitin Modification-dependent Protein Binding Regulation Of Cellular Response To Stress Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Identical Protein Binding G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Negative Regulation Of Store-operated Calcium Channel Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport AnxA2-p11 Complex PCSK9-AnxA2 Complex Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Negative Regulation Of Catabolic Process Negative Regulation Of Receptor Catabolic Process Positive Regulation Of Intracellular Cholesterol Transport Ferritin Complex Ferroxidase Activity Iron Ion Sequestering Activity Protein-containing Complex Cell Adhesion Molecule Production Protein Peptidyl-prolyl Isomerization Negative Regulation Of Protein K48-linked Ubiquitination TRC Complex Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Proteolysis Involved In Protein Catabolic Process Meiotic Recombination Checkpoint Signaling Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Autophagosome Maturation Nuclear Proteasome Complex Positive Regulation Of Low-density Lipoprotein Particle Clearance Negative Regulation Of Transport Positive Regulation Of Plasma Membrane Repair Positive Regulation Of Intracellular Lipid Transport Regulation Of Protein Metabolic Process Mitotic Chromosome Movement Towards Spindle Pole Ribosomal Protein Import Into Nucleus RNA Import Into Nucleus Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep BAT3 Complex Binding Positive Regulation Of Proteasomal Protein Catabolic Process	Positive Regulation Of Metabolic Process Cytosol Regulation Of Long-term Neuronal Synaptic Plasticity Signal Transduction Cytoplasm Regulation Of Defense Response Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cell Communication Negative Regulation Of Transport Ubiquitin Protein Ligase Binding Regulation Of Macromolecule Metabolic Process Regulation Of Neuronal Synaptic Plasticity Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Identical Protein Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Cell Communication Intracellular Receptor Signaling Pathway Postsynapse Negative Regulation Of Endocytosis Regulation Of Signaling Positive Regulation Of Multicellular Organismal Process Regulation Of Multicellular Organismal Process Localization Within Membrane Cytoplasmic Ribonucleoprotein Granule Regulation Of Signal Transduction Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Signaling Negative Regulation Of Chemokine (C-C Motif) Ligand 5 Production Protein Phosphatase Binding Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process Response To Type II Interferon Regulation Of Endocytosis Phosphoprotein Binding Viral RNA Genome Replication Negative Regulation Of Canonical NF-kappaB Signal Transduction Protein Kinase Binding Immune System Process Regulation Of Canonical NF-kappaB Signal Transduction Dendrite Positive Regulation Of Biosynthetic Process Protein Sequestering Activity Protein-macromolecule Adaptor Activity Neuron Projection Lipid Binding Positive Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Cell Adhesion Regulation Of Primary Metabolic Process
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