FTH1 and GOLM1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FTH1	GOLM1
Gene Name		ferritin, heavy polypeptide 1	golgi membrane protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Cytosol Intracellular Ferritin Complex Extracellular Vesicular Exosome	Extracellular Space Golgi Apparatus Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Ferroxidase Activity Iron Ion Binding Protein Binding Ferric Iron Binding	Protein Binding
	Biological Process	Iron Ion Transport Cellular Iron Ion Homeostasis Intracellular Sequestering Of Iron Ion Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Immune Response Negative Regulation Of Cell Proliferation Negative Regulation Of Fibroblast Proliferation Transmembrane Transport Oxidation-reduction Process Membrane Organization	Nucleus Organization Regulation Of Lipid Metabolic Process
Pathways		Iron uptake and transport Golgi Associated Vesicle Biogenesis Scavenging by Class A Receptors trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs		Iron Dextran
Diseases
GWAS		Estradiol levels ( 22675492) Phospholipid levels (plasma) ( 21829377)
Protein-Protein Interactions		31 interactors: BRD7 CD99 CDC16 CDC25A CRMP1 CSF3R CSNK2B DAXX ELL3 FTL FXR2 GOLM1 GRB2 KPNA2 LBP MAX MYL3 NR1I3 NR3C1 NR5A2 PACSIN1 PIAS4 SDCBP SOX5 SPP1 TICAM2 TOLLIP TRAF4 UBR1 WDYHV1 YWHAE	26 interactors: B3GNT4 C1orf174 CIAO1 CLK1 DCK DCTN2 DEXI EFTUD2 EIF2B3 EIF3J ELAC2 FLOT1 FTH1 GEMIN7 GNB2L1 GRIK5 KCNE3 LSM12 MED22 NIPSNAP3A NRSN2 RPA2 RPL13A SLC40A1 SYT1 ZFAND3
Entrez ID		2495	51280
HPRD ID		00615	08428
Ensembl ID		ENSG00000167996	ENSG00000135052
Uniprot IDs		P02794	B3KNK9 Q8NBJ4
PDB IDs		1FHA 2CEI 2CHI 2CIH 2CLU 2CN6 2CN7 2FHA 2IU2 2Z6M 3AJO 3AJP 3AJQ 3ERZ 3ES3 4DYX 4DYY 4DYZ 4DZ0
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Response To Organic Substance Positive Regulation Of Metabolic Process Cellular Response To Stimulus Regulation Of Metabolic Process Chemotaxis Positive Regulation Of Signal Transduction Hormone-mediated Signaling Pathway Response To Stimulus Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Cell Communication Regulation Of Protein Metabolic Process System Development Movement Of Cell Or Subcellular Component Cellular Response To Hormone Stimulus Regulation Of Signal Transduction Generation Of Neurons Anatomical Structure Development Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Toll-like Receptor Signaling Pathway Locomotion Positive Regulation Of Protein Sumoylation Signaling Response To Hormone Neurogenesis Cellular Response To Lipid Leukocyte Migration Signal Transduction Regulation Of Signaling Steroid Hormone Mediated Signaling Pathway Multicellular Organismal Development Regulation Of Protein Sumoylation Response To External Stimulus Leukocyte Chemotaxis Regulation Of Cellular Process Positive Regulation Of Cellular Protein Metabolic Process Developmental Process Positive Regulation Of JNK Cascade Cell Migration Response To Lipid Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Transcription From RNA Polymerase II Promoter Cell Motility Negative Regulation Of Gene Expression	Regulation Of Translational Initiation Negative Regulation Of Translation Regulation Of Translation Negative Regulation Of Translational Initiation Regulation Of Vesicle Fusion Posttranscriptional Regulation Of Gene Expression Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic Negative Regulation Of Formation Of Translation Preinitiation Complex Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Spleen Trabecula Formation Translational Initiation Intracellular Sequestering Of Iron Ion TRNA 3'-trailer Cleavage Positive Regulation Of CAMP Catabolic Process Iron Ion Transport Cellular Iron Ion Homeostasis Dicarboxylic Acid Transport Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Mitochondrial RNA 3'-end Processing Cellular Homeostasis
Tagcloud ?		aggravating anxa1 banks bedside confidently cons ftl gliosis got2 immunochemical infarct infarcted infarcts itraq lagging leak malate mdh2 mortem plex pros proteome proteomics putamen shuttle slc25a11 slc25a12 tca vim	16q 1q affymetrix classic clustering clusters cytoskeleton distinguished epithelium fresh frozen gpr137b hierarchical ilc lcis lobular mastectomy microarrays microdissected obligate personalize pik3r1 precursor prophylactic supervised transcriptomic triplets u133a unsupervised
Tagcloud (Difference) ?		aggravating anxa1 banks bedside confidently cons ftl gliosis got2 immunochemical infarct infarcted infarcts itraq lagging leak malate mdh2 mortem plex pros proteome proteomics putamen shuttle slc25a11 slc25a12 tca vim	16q 1q affymetrix classic clustering clusters cytoskeleton distinguished epithelium fresh frozen gpr137b hierarchical ilc lcis lobular mastectomy microarrays microdissected obligate personalize pik3r1 precursor prophylactic supervised transcriptomic triplets u133a unsupervised
Tagcloud (Intersection) ?