AQP10 and LYVE1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AQP10	LYVE1
Description		aquaporin 10	lymphatic vessel endothelial hyaluronan receptor 1
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GO Annotations	Cellular Component	Lipid Droplet Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane	Plasma Membrane Membrane Extracellular Exosome Cell Periphery
	Molecular Function	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Channel Activity	Transmembrane Signaling Receptor Activity Protein Binding Hyaluronic Acid Binding Signaling Receptor Activity Cargo Receptor Activity
	Biological Process	Water Transport Response To Toxic Substance Glycerol Transmembrane Transport Protein Homotetramerization Transmembrane Transport Urea Transmembrane Transport	Positive Regulation Of Cellular Extravasation Glycosaminoglycan Catabolic Process Receptor-mediated Endocytosis Cell Adhesion Cell-matrix Adhesion Response To Wounding Anatomical Structure Morphogenesis Hyaluronan Catabolic Process
Pathways		Passive transport by Aquaporins	Hyaluronan metabolism Hyaluronan degradation
Drugs			Hyaluronic acid
Diseases
GWAS		Bipolar disorder ( 31043756) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Non-albumin protein levels ( 29403010) Parkinson's disease progression (motor) ( 33111402) Red cell distribution width ( 32888494) Serum total protein levels ( 29403010)	Blood protein levels ( 30072576)
Interacting Genes		20 interacting genes: ARL13B CISD2 CREB3L1 CYBC1 ERGIC3 GPR152 GPR37L1 KIR2DL3 LMNA LYVE1 MGST3 NEMP1 PGRMC2 PLP1 PVR SAR1A SCN3B SSMEM1 SYT2 TMEM167B	26 interacting genes: AIG1 AQP10 CLCN7 CYSRT1 EMP3 KRT34 KRTAP10-3 KRTAP10-8 KRTAP12-3 KRTAP6-2 KRTAP9-2 NBPF19 NINJ2 NOTCH2NLA NRSN1 PDGFB PIGF SERP2 SLC30A2 SLC38A7 SLC41A2 THSD7A THSD7B UBE2J1 VEGFA YIPF6
Entrez ID		89872	10894
HPRD ID		07361	05753
Ensembl ID		ENSG00000143595	ENSG00000133800
Uniprot IDs		Q96PS8	B2R672 Q9Y5Y7
PDB IDs		6F7H	8OS2 8OXD
Enriched GO Terms of Interacting Partners?		Membrane Nuclear Envelope	Intermediate Filament Keratin Filament Positive Regulation Of Protein Autophosphorylation Regulation Of Protein Autophosphorylation Platelet-derived Growth Factor Receptor Binding Monoatomic Cation Transmembrane Transporter Activity
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