MEF2D and CABIN1

Number of citations of the paper that reports this interaction (PMID 15902271)
7

Data Source:
HPRD (in vivo)

		MEF2D	CABIN1
Gene Name		myocyte enhancer factor 2D	calcineurin binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Nucleoplasm Cytoplasm Aggresome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Activating Transcription Factor Binding Histone Deacetylase Binding Protein Dimerization Activity	Protein Phosphatase Inhibitor Activity
	Biological Process	Osteoblast Differentiation Endochondral Ossification Chondrocyte Differentiation Transcription From RNA Polymerase II Promoter Apoptotic Process Nervous System Development Adult Heart Development Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter	DNA Replication-independent Nucleosome Assembly Cell Surface Receptor Signaling Pathway Chromatin Modification Negative Regulation Of Catalytic Activity
Pathways		Organelle biogenesis and maintenance CDO in myogenesis Myogenesis Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis	DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence
Drugs
Diseases
GWAS		Migraine ( 22683712)	Amyotrophic lateral sclerosis ( 23624525)
Protein-Protein Interactions		20 interactors: APP ASCL1 CABIN1 CARM1 CASP7 CDK6 COPS5 EP300 HDAC4 HDAC5 MAPK14 MAPK7 MEF2A MEF2C NFATC2 PRKACA PRMT5 SNCA SP1 YWHAQ	12 interactors: AMPH CALM1 CAMK4 DNM1 H3F3A MEF2B MEF2BNB-MEF2B MEF2D PPP3CA PPP3CB PPP3CC YWHAQ
Entrez ID		4209	23523
HPRD ID		02810	10369
Ensembl ID		ENSG00000116604	ENSG00000099991
Uniprot IDs		Q14814	G5E9F3 Q6PHY0 Q9Y6J0
PDB IDs			1N6J
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Regulation Of Binding Positive Regulation Of Cellular Metabolic Process Cell Activation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Osteoblast Differentiation Signaling Negative Regulation Of Cellular Metabolic Process Cell Communication Immune System Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Defense Response Negative Regulation Of Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Signal Transduction Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Innate Immune Response Negative Regulation Of RNA Biosynthetic Process Regulation Of Ossification Cellular Response To Stimulus Regulation Of Striated Muscle Cell Differentiation Response To Growth Factor Regulation Of Signal Transduction Negative Regulation Of Gene Expression Gene Expression Apoptotic Process Transcription, DNA-templated Programmed Cell Death RNA Biosynthetic Process Organ Development Cell Death Death Regulation Of Signaling Notch Signaling Pathway Response To Organic Substance Cell Surface Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway	Regulation Of Intracellular Transport Positive Regulation Of Intracellular Transport Positive Regulation Of Transport Calcineurin-NFAT Signaling Cascade Regulation Of Cellular Localization Positive Regulation Of NFAT Protein Import Into Nucleus Calcium-mediated Signaling Regulation Of Establishment Of Protein Localization Positive Regulation Of Nucleocytoplasmic Transport Inositol Phosphate-mediated Signaling Regulation Of Protein Localization Second-messenger-mediated Signaling Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Intracellular Protein Transport Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Response To Amphetamine Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Nucleocytoplasmic Transport Synaptic Transmission Substantia Nigra Development Positive Regulation Of Transcription Factor Import Into Nucleus Fc-epsilon Receptor Signaling Pathway Establishment Of Localization In Cell Organ Development System Development Response To Amine Regulation Of Intracellular Protein Transport Regulation Of Transcription, DNA-templated Cell Activation Learning Or Memory Activation Of Phospholipase C Activity Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Fc Receptor Signaling Pathway Regulation Of RNA Biosynthetic Process Muscle Organ Development Neural Nucleus Development Regulation Of RNA Metabolic Process Cellular Response To Drug Positive Regulation Of Phospholipase C Activity Cognition Positive Regulation Of Mitochondrion Organization Innate Immune Response Positive Regulation Of Macromolecule Biosynthetic Process Transition Between Fast And Slow Fiber Positive Regulation Of Protein Transport Multicellular Organismal Development Cellular Localization
Tagcloud ?		blastula distinguished ectoderm ectopic embryo explants lie mef2a mesoderm myf5 myod myogenesis myogenic myosin neither pole precedes presumptive reciprocal rsrf skeletal sl1 sl2 somitic tailbud xenopus xmlc2 zygotic	actively caf calcineurin concomitantly constituting coordinated copyright crosses deposit extractable fertility heterochromatic hir hira impacts imply inheritance nucleosome occupancy orthologs pericentromeric preserve rescues reserved rights transcribed transposons ubinuclein ubn
Tagcloud (Difference) ?		blastula distinguished ectoderm ectopic embryo explants lie mef2a mesoderm myf5 myod myogenesis myogenic myosin neither pole precedes presumptive reciprocal rsrf skeletal sl1 sl2 somitic tailbud xenopus xmlc2 zygotic	actively caf calcineurin concomitantly constituting coordinated copyright crosses deposit extractable fertility heterochromatic hir hira impacts imply inheritance nucleosome occupancy orthologs pericentromeric preserve rescues reserved rights transcribed transposons ubinuclein ubn
Tagcloud (Intersection) ?