CABIN1 and AMPH

Number of citations of the paper that reports this interaction (PMID 10931822)
14

Data Source:
HPRD (in vitro, in vivo)

		CABIN1	AMPH
Gene Name		calcineurin binding protein 1	amphiphysin
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Aggresome	Synaptic Vesicle Actin Cytoskeleton Cell Junction Synaptic Vesicle Membrane Leading Edge Membrane
	Molecular Function	Protein Phosphatase Inhibitor Activity	Protein Binding Phospholipid Binding
	Biological Process	DNA Replication-independent Nucleosome Assembly Cell Surface Receptor Signaling Pathway Chromatin Modification Negative Regulation Of Catalytic Activity	Endocytosis Synaptic Transmission Learning Synaptic Vesicle Endocytosis
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Cellular Senescence
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 23624525)
Protein-Protein Interactions		12 interactors: AMPH CALM1 CAMK4 DNM1 H3F3A MEF2B MEF2BNB-MEF2B MEF2D PPP3CA PPP3CB PPP3CC YWHAQ	27 interactors: AP1B1 AP2A1 AP2A2 ARL16 BIN1 CABIN1 CCDC67 CDK1 CDK5 CDK5R1 CLTC DNM1 DNM2 DYRK1A ITSN2 KHDRBS1 MAPK6 NECAP1 PLD2 PPP3CC SH3GL2 SH3GLB1 SYN1 SYNJ1 TERF1 UBC VTN
Entrez ID		23523	273
HPRD ID		10369	02687
Ensembl ID		ENSG00000099991	ENSG00000078053
Uniprot IDs		G5E9F3 Q6PHY0 Q9Y6J0	P49418
PDB IDs		1N6J	1KY7 1UTC 3SOG 4ATM
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Transport Positive Regulation Of Intracellular Transport Positive Regulation Of Transport Calcineurin-NFAT Signaling Cascade Regulation Of Cellular Localization Positive Regulation Of NFAT Protein Import Into Nucleus Calcium-mediated Signaling Regulation Of Establishment Of Protein Localization Positive Regulation Of Nucleocytoplasmic Transport Inositol Phosphate-mediated Signaling Regulation Of Protein Localization Second-messenger-mediated Signaling Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Intracellular Protein Transport Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Response To Amphetamine Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Nucleocytoplasmic Transport Synaptic Transmission Substantia Nigra Development Positive Regulation Of Transcription Factor Import Into Nucleus Fc-epsilon Receptor Signaling Pathway Establishment Of Localization In Cell Organ Development System Development Response To Amine Regulation Of Intracellular Protein Transport Regulation Of Transcription, DNA-templated Cell Activation Learning Or Memory Activation Of Phospholipase C Activity Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Fc Receptor Signaling Pathway Regulation Of RNA Biosynthetic Process Muscle Organ Development Neural Nucleus Development Regulation Of RNA Metabolic Process Cellular Response To Drug Positive Regulation Of Phospholipase C Activity Cognition Positive Regulation Of Mitochondrion Organization Innate Immune Response Positive Regulation Of Macromolecule Biosynthetic Process Transition Between Fast And Slow Fiber Positive Regulation Of Protein Transport Multicellular Organismal Development Cellular Localization	Endocytosis Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Receptor Metabolic Process Post-Golgi Vesicle-mediated Transport Synaptic Vesicle Recycling Receptor-mediated Endocytosis Synaptic Vesicle Transport Receptor Internalization Regulation Of Signaling Synaptic Transmission Axon Guidance Peptidyl-threonine Phosphorylation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of ERBB Signaling Pathway Neuron Projection Morphogenesis Positive Regulation Of Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Axonogenesis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Neuron Projection Development Axon Development Regulation Of Signal Transduction Cell Projection Morphogenesis Establishment Of Vesicle Localization Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Defense Response To Virus By Virus Positive Regulation Of Apoptotic Process Regulation Of Vesicle-mediated Transport Positive Regulation Of Programmed Cell Death Cell Part Morphogenesis Chemotaxis Vesicle Localization Regulation Of Cellular Component Organization Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Hyaluronan Biosynthetic Process Cellular Localization Positive Regulation Of Cell Death Ephrin Receptor Signaling Pathway Regulation Of Cell Cycle Arrest Neurotrophin Signaling Pathway Establishment Of Localization In Cell
Tagcloud ?		actively caf calcineurin concomitantly constituting coordinated copyright crosses deposit extractable fertility heterochromatic hir hira impacts imply inheritance nucleosome occupancy orthologs pericentromeric preserve rescues reserved rights transcribed transposons ubinuclein ubn	10a 10as 6b 6br 7h amphetamine antipsychotic butan cataleptogenic demonstrable dimethoxy headtwitch hexahydro histaminergic ht2a ht2c hydrochloride hyperlocomotion id50 iodoamphetamine mesocortical mesolimbic microdialysis neurotransmission pyrido pyrrolo quinoxalin sert unwanted
Tagcloud (Difference) ?		actively caf calcineurin concomitantly constituting coordinated copyright crosses deposit extractable fertility heterochromatic hir hira impacts imply inheritance nucleosome occupancy orthologs pericentromeric preserve rescues reserved rights transcribed transposons ubinuclein ubn	10a 10as 6b 6br 7h amphetamine antipsychotic butan cataleptogenic demonstrable dimethoxy headtwitch hexahydro histaminergic ht2a ht2c hydrochloride hyperlocomotion id50 iodoamphetamine mesocortical mesolimbic microdialysis neurotransmission pyrido pyrrolo quinoxalin sert unwanted
Tagcloud (Intersection) ?