STX19 and STXBP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		STX19	STXBP1
Gene Name		syntaxin 19	syntaxin binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex	Nucleoplasm Cytoplasm Mitochondrion Cytosol Plasma Membrane Platelet Alpha Granule Protein Complex Extracellular Vesicular Exosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	SNARE Binding Syntaxin-1 Binding Protein Kinase Binding Protein Domain Specific Binding Syntaxin Binding Identical Protein Binding Poly(A) RNA Binding Protein N-terminus Binding
	Biological Process	Intracellular Protein Transport Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking	Platelet Degranulation Energy Reserve Metabolic Process Vesicle Docking Involved In Exocytosis Synaptic Transmission Neurotransmitter Secretion Neuromuscular Synaptic Transmission Axon Target Recognition Regulation Of Synaptic Vesicle Priming Glutamate Secretion Protein Transport Synaptic Vesicle Maturation Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Negative Regulation Of Synaptic Transmission, GABAergic Regulation Of SNARE Complex Assembly Negative Regulation Of Neuron Apoptotic Process Small Molecule Metabolic Process Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Insulin Secretion Protein Stabilization Long Term Synaptic Depression Platelet Aggregation Protein Localization To Plasma Membrane
Pathways			Integration of energy metabolism Regulation of insulin secretion
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: KDM1A PRKAB2 STXBP1 SUV39H1 SYCE1	27 interactors: APBA1 APBA2 APP CDK5 CDK5R1 DOC2A DOC2B DYT10 HGS MAPT NEFH NEFM PLD1 PLD2 PRKCA PRKCB PRKCG SQSTM1 STX11 STX19 STX1A STX1B STX2 STX3 SYTL4 TRIM38 USO1
Entrez ID		415117	6812
HPRD ID		14477	04235
Ensembl ID		ENSG00000178750	ENSG00000136854
Uniprot IDs		Q8N4C7	B7Z1V5 P61764 Q68CM6
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Regulation Of Primitive Erythrocyte Differentiation Energy Reserve Metabolic Process Chromosome Organization Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Axon Target Recognition Histone H3-K9 Dimethylation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Negative Regulation Of Synaptic Transmission, GABAergic Histone H3-K4 Demethylation Regulation Of SNARE Complex Assembly Energy Derivation By Oxidation Of Organic Compounds Carboxylic Acid Transport Organic Acid Transport Cell Cycle Regulation Of Synaptic Vesicle Priming Carnitine Shuttle Positive Regulation Of Megakaryocyte Differentiation Histone H3-K9 Trimethylation Carnitine Transmembrane Transport Oxidation-reduction Process Positive Regulation Of Hormone Biosynthetic Process Carnitine Transport Peptidyl-lysine Dimethylation Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Histone Modification Synaptic Vesicle Maturation Generation Of Precursor Metabolites And Energy Blood Coagulation Hemostasis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Organic Anion Transport Chromatin Silencing At RDNA Granulocyte Differentiation Long Term Synaptic Depression Positive Regulation Of Calcium Ion-dependent Exocytosis Quaternary Ammonium Group Transport Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Erythrocyte Differentiation Negative Regulation Of Circadian Rhythm Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Histone H3-K9 Methylation Regulation Of Histone H3-K4 Methylation Synaptonemal Complex Assembly Neuromuscular Synaptic Transmission Glutamate Secretion	Synaptic Transmission Synaptic Vesicle Exocytosis Synaptic Vesicle Fusion To Presynaptic Membrane Neurotransmitter Secretion Synaptic Vesicle Transport Cell-cell Signaling Regulation Of Neurotransmitter Levels Establishment Of Localization In Cell Secretion By Cell Neurotransmitter Transport Vesicle Fusion Establishment Of Vesicle Localization Vesicle Localization Secretion Establishment Of Organelle Localization Cellular Localization Exocytosis Organelle Fusion Vesicle Docking Intracellular Transport Membrane Docking Organelle Localization Membrane Fusion Protein Localization Regulation Of Exocytosis Regulation Of Cellular Localization Protein Transport Membrane Organization Establishment Of Protein Localization Intracellular Protein Transport Signaling Transport Cell Communication Vesicle Organization Positive Regulation Of Exocytosis Vesicle-mediated Transport Cellular Protein Localization Regulation Of Vesicle-mediated Transport Peptidyl-threonine Phosphorylation Regulation Of Secretion Axon Cargo Transport Regulation Of Signaling Organelle Organization Positive Regulation Of Secretion Histone H3-T6 Phosphorylation Neurofilament Bundle Assembly Positive Regulation Of Transport Serine Phosphorylation Of STAT3 Protein Nervous System Development Regulation Of Synaptic Vesicle Transport
Tagcloud ?			16p12 2q24 5q14 9q34 aetiology caln1 cdkl5 cgh cnv cnvs counselling ehmt1 encephalopathies encompassing epileptic etiological grin2a hypsarrhythmia infantile intronic iss kcnq2 magi2 mef2c microdeletions microduplications scn2a spasms xq28
Tagcloud (Difference) ?			16p12 2q24 5q14 9q34 aetiology caln1 cdkl5 cgh cnv cnvs counselling ehmt1 encephalopathies encompassing epileptic etiological grin2a hypsarrhythmia infantile intronic iss kcnq2 magi2 mef2c microdeletions microduplications scn2a spasms xq28
Tagcloud (Intersection) ?