MIR214 and RBM10

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR214	RBM10
Description		microRNA 214	RNA binding motif protein 10
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus RISC Complex Perinuclear Region Of Cytoplasm Extracellular Vesicle	Nucleus Nucleoplasm Nucleolus Nuclear Speck Protein-containing Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding MiRNA Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Lamellipodium Assembly Negative Regulation Of Gene Expression Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Chemokine Production MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Necroptotic Process Cellular Response To Hypoxia Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation Positive Regulation Of Connective Tissue Replacement	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome MRNA Processing Negative Regulation Of Cell Population Proliferation RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome 3'-UTR-mediated MRNA Stabilization Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Vascular Associated Smooth Muscle Cell Apoptotic Process Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Ribosomal Large Subunit Export From Nucleus
Pathways			mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases			TARP syndrome
GWAS		Height ( 31562340)
Interacting Genes		92 interacting genes: AIMP1 AIMP2 AQR ATXN2L C1QBP CDC5L CELF1 CPSF1 DARS1 DDX1 DDX21 DDX23 DDX3X DDX49 DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PTBP1 PTCD3 PUF60 PUM1 PUM2 QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM4 RBM4B RTCA RTCB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZC3H11A ZFR ZNF346	73 interacting genes: AKAP9 ATN1 BAHD1 BEND7 CASK CBLL1 CCAR1 CEP70 CPSF7 CSNK2A1 DDX17 DDX5 FAM124A GTSE1 HNRNPH2 HNRNPK HNRNPLL IK KHDRBS2 KLF1 MAPRE2 MBD6 MDM2 MEOX2 MIR106B MIR107 MIR128-1 MIR21 MIR214 MIRLET7A1 MIRLET7A3 MIRLET7D MIRLET7E MIRLET7G MIRLET7I NDEL1 NIN PATZ1 PCBP1 PRC1 PRCC PRDM14 PRR20A PTBP1 PTBP2 RBM12 RBM12B RBM14 RBM4 RBM7 RBMY1F RNF10 SF1 SF3A1 SF3B2 SF3B4 SLAIN1 SNRPA SNU13 SREK1 SRSF6 TBC1D22B THAP1 TLE5 U2AF1 UBQLN4 ZBTB24 ZFP64 ZNF275 ZNF317 ZNF408 ZNF473 ZNF526
Entrez ID		406996	8241
HPRD ID			02095
Ensembl ID		ENSG00000283844	ENSG00000182872
Uniprot IDs			A0A0S2Z4W4 A0A0S2Z4X1 P98175
PDB IDs			2LXI 2M2B 2MXV 2MXW 5ZSW 5ZSY
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process MRNA Binding MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Macromolecule Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Post-transcriptional Regulation Of Gene Expression Catalytic Step 2 Spliceosome Nucleoplasm Nucleus Spliceosomal Complex Cytoplasmic Stress Granule Regulation Of MRNA Processing MiRNA Binding Regulation Of MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Regulation Of Translation Negative Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding Regulation Of RNA Stability Regulation Of MRNA Stability Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleolus TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process RNA Helicase Activity Negative Regulation Of Translation Positive Regulation Of Cytoplasmic Translation RNA Transport Positive Regulation Of Gene Expression Ligase Activity CRD-mediated MRNA Stabilization MRNA 5'-UTR Binding	MRNA Processing MRNA Metabolic Process Regulation Of RNA Splicing Nucleic Acid Binding RNA Splicing Regulatory NcRNA-mediated Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RNA Processing Post-transcriptional Gene Silencing Spliceosomal Complex MRNA Splicing, Via Spliceosome MRNA Base-pairing Post-transcriptional Repressor Activity RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome RNA Binding MRNA Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Gene Expression Negative Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleoplasm Nuclear Speck Regulation Of Macromolecule Metabolic Process Nucleic Acid Metabolic Process Regulation Of Primary Metabolic Process Nucleus Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Extracellular Vesicle Negative Regulation Of Translation Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Ribonucleoprotein Complex Pre-mRNA Binding MRNA 3'-UTR Binding Post-transcriptional Regulation Of Gene Expression U2-type Precatalytic Spliceosome Negative Regulation Of RNA Splicing Microtubule Nucleation
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