MIR19B2 and ZNF385A

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR19B2	ZNF385A
Description		microRNA 19b-2	zinc finger protein 385A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	RISC Complex	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Dendrite Cell Projection Neuronal Cell Body
	Molecular Function		P53 Binding Nucleic Acid Binding DNA Binding RNA Binding MRNA 3'-UTR Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing	Regulation Of Translation Apoptotic Process DNA Damage Response Hemostasis Learning Or Memory Locomotory Behavior Intracellular MRNA Localization MRNA Localization Resulting In Post-transcriptional Regulation Of Gene Expression Platelet Formation Megakaryocyte Development Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Fat Cell Differentiation Platelet Alpha Granule Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Cytoplasmic Translation
Pathways			TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Regulation of TP53 Activity through Association with Co-factors Transcriptional activation of cell cycle inhibitor p21
Drugs
Diseases
GWAS			Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		93 interacting genes: ADARB1 AIMP1 AIMP2 AQR C1QBP CELF1 CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 ESRP1 FAM98A FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PATL1 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 QKI RARS1 RBFOX2 RBM14 RBM4 RBMS2 RTCA RTCB SART3 SF1 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2B TRIM25 U2SURP UPF1 USP36 UTP20 YBX1 YBX3 ZFR ZNF346 ZNF385A	10 interacting genes: MIR1-1 MIR155 MIR19A MIR19B1 MIR19B2 MIR34C MIR9-1 MIR9-2 MIR9-3 OGT
Entrez ID		406981	25946
HPRD ID			16448
Ensembl ID		ENSG00000284107	ENSG00000161642
Uniprot IDs			Q96PM9
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process MRNA Binding Nucleobase-containing Compound Metabolic Process Nucleus MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleoplasm Post-transcriptional Regulation Of Gene Expression Ribonucleoprotein Complex Spliceosomal Complex MRNA 3'-UTR Binding Catalytic Step 2 Spliceosome Regulation Of Translation MiRNA Binding Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Translation Regulation Of Gene Expression Negative Regulation Of RNA Catabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity RNA Stabilization TRNA Aminoacylation Regulation Of Macromolecule Metabolic Process Regulation Of MRNA Stability MRNA Stabilization Ligase Activity Regulation Of RNA Stability Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Nucleolus Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Helicase Activity Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cytoplasmic Translation	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing RISC Complex Post-transcriptional Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Metabolic Process Negative Regulation Of Extracellular Matrix Assembly Regulation Of Cardiac Muscle Hypertrophy MRNA Destabilization Regulation Of Extracellular Matrix Assembly RNA Destabilization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Extracellular Matrix Organization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Negative Regulation Of Response To Drug Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of MRNA Stability Regulation Of Sprouting Angiogenesis Regulation Of RNA Stability Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Developmental Process Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Heart Growth Regulation Of Extracellular Matrix Organization Regulation Of Response To Drug Regulation Of Muscle System Process Positive Regulation Of Muscle Cell Differentiation Regulation Of Macromolecule Metabolic Process
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