ZNF385A and MIR9-1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		ZNF385A	MIR9-1
Description		zinc finger protein 385A	microRNA 9-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Dendrite Cell Projection Neuronal Cell Body	Nucleus Cytoplasm RISC Complex Extracellular Exosome
	Molecular Function	P53 Binding Nucleic Acid Binding DNA Binding RNA Binding MRNA 3'-UTR Binding Zinc Ion Binding Metal Ion Binding	Single-stranded RNA Binding MRNA 3'-UTR Binding High-density Lipoprotein Particle Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Regulation Of Translation Apoptotic Process DNA Damage Response Hemostasis Learning Or Memory Locomotory Behavior Intracellular MRNA Localization MRNA Localization Resulting In Post-transcriptional Regulation Of Gene Expression Platelet Formation Megakaryocyte Development Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Fat Cell Differentiation Platelet Alpha Granule Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Cytoplasmic Translation	Negative Regulation Of Cell Adhesion Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulatory NcRNA-mediated Gene Silencing Negative Regulation Of Osteoblast Proliferation MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Lipid Biosynthetic Process Negative Regulation Of Cholesterol Efflux Negative Regulation Of Extracellular Matrix Assembly Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Lymphangiogenesis Negative Regulation Of Myofibroblast Differentiation Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways		TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Regulation of TP53 Activity through Association with Co-factors Transcriptional activation of cell cycle inhibitor p21
Drugs
Diseases
GWAS		Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: MIR1-1 MIR155 MIR19A MIR19B1 MIR19B2 MIR34C MIR9-1 MIR9-2 MIR9-3 OGT	84 interacting genes: ADARB1 APOBEC3B C1QBP CELF1 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS GRSF1 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 PDCD11 PLOD1 PRMT1 PTBP1 PUF60 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3 ZC3H11A ZFR ZNF346 ZNF385A
Entrez ID		25946	407046
HPRD ID		16448
Ensembl ID		ENSG00000161642	ENSG00000207933
Uniprot IDs		Q96PM9
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing RISC Complex Post-transcriptional Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Metabolic Process Negative Regulation Of Extracellular Matrix Assembly Regulation Of Cardiac Muscle Hypertrophy MRNA Destabilization Regulation Of Extracellular Matrix Assembly RNA Destabilization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Extracellular Matrix Organization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Negative Regulation Of Response To Drug Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of MRNA Stability Regulation Of Sprouting Angiogenesis Regulation Of RNA Stability Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Developmental Process Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Heart Growth Regulation Of Extracellular Matrix Organization Regulation Of Response To Drug Regulation Of Muscle System Process Positive Regulation Of Muscle Cell Differentiation Regulation Of Macromolecule Metabolic Process	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Macromolecule Metabolic Process Ribonucleoprotein Complex Nucleus Nucleoplasm MRNA Splicing, Via Spliceosome Post-transcriptional Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Catalytic Step 2 Spliceosome Negative Regulation Of RNA Catabolic Process MiRNA Binding TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Gene Expression TRNA Aminoacylation TRNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Cytoplasmic Stress Granule Positive Regulation Of Gene Expression Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Catabolic Process Negative Regulation Of Translation RNA Stabilization Regulation Of Primary Metabolic Process Ligase Activity Regulation Of RNA Stability MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleolus Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process
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