ZNF385A

Description		zinc finger protein 385A
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Dendrite Cell Projection Neuronal Cell Body
	Molecular Function	P53 Binding Nucleic Acid Binding DNA Binding RNA Binding MRNA 3'-UTR Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Translation Apoptotic Process DNA Damage Response Hemostasis Learning Or Memory Locomotory Behavior Intracellular MRNA Localization MRNA Localization Resulting In Post-transcriptional Regulation Of Gene Expression Platelet Formation Megakaryocyte Development Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Fat Cell Differentiation Platelet Alpha Granule Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Cytoplasmic Translation
Pathways		TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Regulation of TP53 Activity through Association with Co-factors Transcriptional activation of cell cycle inhibitor p21
Drugs
Diseases
GWAS		Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: MIR1-1 MIR155 MIR19A MIR19B1 MIR19B2 MIR34C MIR9-1 MIR9-2 MIR9-3 OGT
Entrez ID		25946
HPRD ID		16448
Ensembl ID		ENSG00000161642
Uniprot IDs		Q96PM9
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing RISC Complex Post-transcriptional Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Metabolic Process Negative Regulation Of Extracellular Matrix Assembly Regulation Of Cardiac Muscle Hypertrophy MRNA Destabilization Regulation Of Extracellular Matrix Assembly RNA Destabilization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Extracellular Matrix Organization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Negative Regulation Of Response To Drug Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of MRNA Stability Regulation Of Sprouting Angiogenesis Regulation Of RNA Stability Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Developmental Process Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Heart Growth Regulation Of Extracellular Matrix Organization Regulation Of Response To Drug Regulation Of Muscle System Process Positive Regulation Of Muscle Cell Differentiation Regulation Of Macromolecule Metabolic Process
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