MIR19B2 and U2SURP

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR19B2	U2SURP
Description		microRNA 19b-2	U2 snRNP associated SURP domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	RISC Complex	Nucleus Nucleoplasm U2 SnRNP
	Molecular Function		Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing	RNA Processing
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean platelet volume ( 32888494) Urate levels ( 31578528)
Interacting Genes		93 interacting genes: ADARB1 AIMP1 AIMP2 AQR C1QBP CELF1 CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 ESRP1 FAM98A FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PATL1 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 QKI RARS1 RBFOX2 RBM14 RBM4 RBMS2 RTCA RTCB SART3 SF1 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2B TRIM25 U2SURP UPF1 USP36 UTP20 YBX1 YBX3 ZFR ZNF346 ZNF385A	63 interacting genes: CEBPA CTNNBL1 DDX42 H19 MIR1-1 MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR143 MIR145 MIR155 MIR15B MIR18A MIR18B MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200B MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR92A1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PRPF40A RNF10 TBC1D4 TERT TRA2A
Entrez ID		406981	23350
HPRD ID			19056
Ensembl ID		ENSG00000284107	ENSG00000163714
Uniprot IDs			O15042
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process MRNA Binding Nucleobase-containing Compound Metabolic Process Nucleus MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleoplasm Post-transcriptional Regulation Of Gene Expression Ribonucleoprotein Complex Spliceosomal Complex MRNA 3'-UTR Binding Catalytic Step 2 Spliceosome Regulation Of Translation MiRNA Binding Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Translation Regulation Of Gene Expression Negative Regulation Of RNA Catabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity RNA Stabilization TRNA Aminoacylation Regulation Of Macromolecule Metabolic Process Regulation Of MRNA Stability MRNA Stabilization Ligase Activity Regulation Of RNA Stability Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Nucleolus Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Helicase Activity Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cytoplasmic Translation	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MRNA Destabilization RNA Destabilization Extracellular Vesicle Positive Regulation Of MRNA Catabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of MRNA Stability Negative Regulation Of Angiogenesis Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Macromolecule Biosynthetic Process Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Regulation Of RNA Stability Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Developmental Process Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Translation Regulation Of Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Negative Regulation Of Signal Transduction Regulation Of Cell Motility Negative Regulation Of Protein Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Anatomical Structure Morphogenesis Regulation Of Locomotion Regulation Of Endothelial Cell Migration Positive Regulation Of Catabolic Process
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