MIR138-1 and ESRP1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR138-1	ESRP1
Description		microRNA 138-1	epithelial splicing regulatory protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm RISC Complex	Nucleus Nucleoplasm Nuclear Body Ribonucleoprotein Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Negative Regulation Of Cell Adhesion Negative Regulation Of Cell Population Proliferation Negative Regulation Of Lipid Storage Negative Regulation Of Cell Migration Negative Regulation Of Osteoblast Proliferation MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Vasodilation Negative Regulation Of Canonical NF-kappaB Signal Transduction Plasma Membrane Raft Assembly Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Inflammatory Response Negative Regulation Of Stress Fiber Assembly Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Response To Cytokine Stimulus Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of Adipose Tissue Development Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process	MRNA Processing RNA Splicing Regulation Of Inner Ear Auditory Receptor Cell Fate Specification Regulation Of RNA Splicing
Pathways			Signaling by BRAF and RAF1 fusions FGFR2 alternative splicing
Drugs
Diseases
GWAS		Schizophrenia ( 30285260)	Abstraction and mental flexibility ( 31596458) Urate levels ( 31578528)
Interacting Genes		67 interacting genes: ADARB1 C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LRPPRC MARS1 MATR3 NONO NUDT16L1 NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUM1 QARS1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3	49 interacting genes: ALG13 ARID5A ATXN1 DAZAP2 H19 KLHDC7B KRTAP19-5 MED25 MIR106A MIR106B MIR128-2 MIR138-1 MIR138-2 MIR141 MIR155 MIR15B MIR19B1 MIR19B2 MIR200A MIR200C MIR20B MIR21 MIR222 MIR25 MIR29C MIR34A MIR34B MIR363 MIR7-1 MIR9-1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7F2 MIRLET7G MIRLET7I MRPS24 OXER1 PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS2 ZC3H10
Entrez ID		406929	54845
HPRD ID			07881
Ensembl ID		ENSG00000207954	ENSG00000104413
Uniprot IDs			A0A2U3TZN9 Q6NXG1
PDB IDs			2DHA 2RVJ 7VKI 7VKJ 7WRN
Enriched GO Terms of Interacting Partners?		RNA Binding RNA Processing Nucleic Acid Binding RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process MRNA Binding Regulation Of RNA Splicing Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Post-transcriptional Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Nucleus Ribonucleoprotein Complex Nucleoplasm Spliceosomal Complex Negative Regulation Of MRNA Metabolic Process Catalytic Step 2 Spliceosome Regulation Of Gene Expression Negative Regulation Of RNA Catabolic Process Regulation Of Macromolecule Biosynthetic Process MRNA 3'-UTR Binding Aminoacyl-tRNA Synthetase Multienzyme Complex MiRNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Translation Cytoplasmic Stress Granule Regulation Of MRNA Processing Positive Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process MRNA Stabilization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation Regulation Of MRNA Stability Positive Regulation Of Macromolecule Metabolic Process Regulation Of RNA Stability Positive Regulation Of Cytoplasmic Translation Negative Regulation Of Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Extracellular Vesicle MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MRNA Destabilization Negative Regulation Of Translation RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of MRNA Stability Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Regulation Of MRNA Metabolic Process Regulation Of Vascular Endothelial Cell Proliferation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Translation Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Cytokine Production Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Endothelial Cell Proliferation Regulation Of Endothelial Cell Proliferation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Endothelial Cell Migration Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Vasculature Development Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Signal Transduction Negative Regulation Of Locomotion Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
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