MIR138-1 and FAM98B

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR138-1	FAM98B
Description		microRNA 138-1	family with sequence similarity 98 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm RISC Complex	Nucleus Nucleoplasm Cytoplasm TRNA-splicing Ligase Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	RNA Binding Protein Binding Protein Methyltransferase Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Cell Adhesion Negative Regulation Of Cell Population Proliferation Negative Regulation Of Lipid Storage Negative Regulation Of Cell Migration Negative Regulation Of Osteoblast Proliferation MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Vasodilation Negative Regulation Of Canonical NF-kappaB Signal Transduction Plasma Membrane Raft Assembly Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Inflammatory Response Negative Regulation Of Stress Fiber Assembly Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Response To Cytokine Stimulus Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of Adipose Tissue Development Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Protein Methylation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression
Pathways			tRNA processing in the nucleus
Drugs
Diseases
GWAS		Schizophrenia ( 30285260)	Psychosis (atypical) ( 24132900) Systemic lupus erythematosus ( 24871463)
Interacting Genes		67 interacting genes: ADARB1 C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LRPPRC MARS1 MATR3 NONO NUDT16L1 NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUM1 QARS1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3	21 interacting genes: CEBPA MIR106A MIR10B MIR138-1 MIR141 MIR16-1 MIR18B MIR199A2 MIR200B MIR200C MIR205 MIR222 MIR34A MIR7-3 MIR9-1 MIRLET7A1 MIRLET7A2 MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G
Entrez ID		406929	283742
HPRD ID			08786
Ensembl ID		ENSG00000207954	ENSG00000171262
Uniprot IDs			Q52LJ0
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding RNA Processing Nucleic Acid Binding RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process MRNA Binding Regulation Of RNA Splicing Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Post-transcriptional Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Nucleus Ribonucleoprotein Complex Nucleoplasm Spliceosomal Complex Negative Regulation Of MRNA Metabolic Process Catalytic Step 2 Spliceosome Regulation Of Gene Expression Negative Regulation Of RNA Catabolic Process Regulation Of Macromolecule Biosynthetic Process MRNA 3'-UTR Binding Aminoacyl-tRNA Synthetase Multienzyme Complex MiRNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Translation Cytoplasmic Stress Granule Regulation Of MRNA Processing Positive Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process MRNA Stabilization Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation Regulation Of MRNA Stability Positive Regulation Of Macromolecule Metabolic Process Regulation Of RNA Stability Positive Regulation Of Cytoplasmic Translation Negative Regulation Of Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Translation Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Locomotion Regulation Of Cell Migration Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Metabolic Process Regulation Of Cell Motility Negative Regulation Of Protein Metabolic Process Regulation Of Locomotion Negative Regulation Of Vascular Endothelial Growth Factor Production MRNA Destabilization RNA Destabilization Regulation Of Endothelial Cell Migration Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cytokine Production Negative Regulation Of Developmental Process Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Positive Regulation Of MRNA Metabolic Process Regulation Of Osteoblast Differentiation Negative Regulation Of Endothelial Cell Migration Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
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