MIR10B and LSM10

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR10B	LSM10
Description		microRNA 10b	LSM10, U7 small nuclear RNA associated
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex Extracellular Exosome	Nucleus Nucleoplasm U7 SnRNP Cajal Body Nuclear Body Cytoplasmic U SnRNP Body Ribonucleoprotein Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	RNA Binding Protein Binding Histone Pre-mRNA DCP Binding U7 SnRNA Binding
	Biological Process	Positive Regulation Of Lipid Storage Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis	MRNA Processing MRNA 3'-end Processing By Stem-loop Binding And Cleavage RNA Splicing Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Systolic blood pressure ( 27841878 30578418)	Diverticulitis ( 28585551) Neutrophil count ( 29403010)
Interacting Genes		80 interacting genes: APOBEC3B ATXN2L C1QBP CELF1 CPSF6 CPSF7 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FAM98B FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC LSM10 LSM11 MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SYNCRIP TAF15 TENT2 TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346	10 interacting genes: BMPR2 CLNS1A LSM11 LSM3 MIR10B MIR128-1 MIR20A MIRLET7A1 SLBP SMN1
Entrez ID		406903	84967
HPRD ID			14326
Ensembl ID		ENSG00000207744	ENSG00000181817
Uniprot IDs			Q969L4
PDB IDs			6V4X
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Ribonucleoprotein Complex Regulation Of RNA Splicing Nucleus MRNA Splicing, Via Spliceosome Nucleoplasm Post-transcriptional Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Aminoacyl-tRNA Synthetase Multienzyme Complex Catalytic Step 2 Spliceosome Spliceosomal Complex Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process MRNA 3'-UTR Binding Positive Regulation Of Gene Expression Negative Regulation Of Translation Negative Regulation Of MRNA Catabolic Process RNA Stabilization MiRNA Binding TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Gene Expression Regulation Of RNA Stability TRNA Aminoacylation MRNA Stabilization Regulation Of Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome TRNA Metabolic Process Regulation Of MRNA Stability Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cytoplasmic Translation RNA 3'-end Processing Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process	MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Positive Regulation Of MRNA Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulatory NcRNA-mediated Gene Silencing MRNA Processing Negative Regulation Of Translation Regulation Of Cell Migration Involved In Sprouting Angiogenesis MRNA 3'-end Processing By Stem-loop Binding And Cleavage Histone Pre-mRNA 3'end Processing Complex MRNA Metabolic Process MRNA Destabilization RNA Destabilization Regulation Of MRNA Metabolic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Proliferation Involved In Heart Morphogenesis MRNA 3'-UTR Binding RNA Processing Regulation Of Translation Histone MRNA Metabolic Process Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Cell Migration Regulation Of Cell Motility MRNA 3'-end Processing Regulation Of Endothelial Cell Migration Regulation Of MRNA Stability Regulation Of Locomotion RNA Splicing, Via Transesterification Reactions Regulation Of RNA Stability Negative Regulation Of Protein Metabolic Process Post-transcriptional Regulation Of Gene Expression Spliceosomal SnRNP Assembly Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Outflow Tract Morphogenesis Negative Regulation Of Lipoprotein Transport Negative Regulation Of Cardioblast Proliferation RNA Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Osteoblast Differentiation Extracellular Space Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility
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