MIR10B and CRTAP

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR10B	CRTAP
Description		microRNA 10b	cartilage associated protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex Extracellular Exosome	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Protein-containing Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Protein Binding Collagen Binding
	Biological Process	Positive Regulation Of Lipid Storage Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis	Protein Folding Spermatogenesis Collagen Fibril Organization Protein Stabilization Negative Regulation Of Post-translational Protein Modification
Pathways			Collagen biosynthesis and modifying enzymes
Drugs
Diseases			Osteogenesis imperfecta
GWAS		Diastolic blood pressure ( 27841878) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Systolic blood pressure ( 27841878 30578418)	Asthma ( 31619474 31959851) Femur bone mineral density x serum urate levels interaction ( 34046847) Major depressive disorder ( 29317602) Multiple sclerosis ( 31604244) Refractive error ( 32231278) Retinal detachment or retinal break ( 31816047)
Interacting Genes		80 interacting genes: APOBEC3B ATXN2L C1QBP CELF1 CPSF6 CPSF7 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FAM98B FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC LSM10 LSM11 MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SYNCRIP TAF15 TENT2 TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346	26 interacting genes: MIR1-1 MIR10B MIR128-1 MIR138-2 MIR140 MIR16-1 MIR16-2 MIR17 MIR18A MIR199A2 MIR19A MIR19B1 MIR200B MIR200C MIR20A MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIRLET7B MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I OGT RIPPLY3
Entrez ID		406903	10491
HPRD ID			16110
Ensembl ID		ENSG00000207744	ENSG00000170275
Uniprot IDs			C9JP16 O75718
PDB IDs			8K0E 8K0F 8K0I 8K0M 8K17 8KC9
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Ribonucleoprotein Complex Regulation Of RNA Splicing Nucleus MRNA Splicing, Via Spliceosome Nucleoplasm Post-transcriptional Regulation Of Gene Expression RNA Splicing, Via Transesterification Reactions Aminoacyl-tRNA Synthetase Multienzyme Complex Catalytic Step 2 Spliceosome Spliceosomal Complex Cytoplasmic Stress Granule Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process MRNA 3'-UTR Binding Positive Regulation Of Gene Expression Negative Regulation Of Translation Negative Regulation Of MRNA Catabolic Process RNA Stabilization MiRNA Binding TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Gene Expression Regulation Of RNA Stability TRNA Aminoacylation MRNA Stabilization Regulation Of Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome TRNA Metabolic Process Regulation Of MRNA Stability Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cytoplasmic Translation RNA 3'-end Processing Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process	RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Translation Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of MRNA Stability Regulation Of RNA Stability Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Translation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of MRNA Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Macromolecule Metabolic Process Extracellular Vesicle Negative Regulation Of Protein Metabolic Process Regulation Of Cell Migration Regulation Of Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Catabolic Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Signal Transduction Negative Regulation Of Endothelial Cell Migration Extracellular Space Regulation Of Angiogenesis Negative Regulation Of Cell Communication
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