MIR107 and RBM17

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR107	RBM17
Description		microRNA 107	RNA binding motif protein 17
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex Neuronal Cell Body Extracellular Vesicle	Nucleus Nucleoplasm Spliceosomal Complex Protein-containing Complex
	Molecular Function	MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Cellular Response To Insulin Stimulus MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Gluconeogenesis Negative Regulation Of D-glucose Import Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Necroptotic Process Cellular Response To Hydrogen Peroxide Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing MRNA Cis Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474 31959851) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Brooding (response to stress) ( 30886212) Crohn's disease ( 28067908) Diisocyanate-induced asthma ( 25918132) Multiple sclerosis ( 24076602) Soluble interleukin-2 receptor subunit alpha ( 26293465) Vitiligo ( 20410501)
Interacting Genes		83 interacting genes: AIMP1 AIMP2 AQR C1QBP CDC5L CELF1 CPSF1 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT21 NUFIP2 P3H1 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PUM1 QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM17 RTCB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3 ZNF346	33 interacting genes: APBB1 C6orf47 CCDC170 CCHCR1 CEBPA CEP55 CSNK2A1 CWC15 FAM9B GOLGA2 HINFP HSF2BP IQCN LNX2 MIR106B MIR107 MIR128-1 MIR155 MIR21 MIR25 MIRLET7A2 MIRLET7G MIRLET7I OGT PPP1R12C PRC1 QRICH1 RBFOX2 SAP30BP SAT1 SF1 SF3B1 TNS3
Entrez ID		406901	84991
HPRD ID			09501
Ensembl ID		ENSG00000198997	ENSG00000134453
Uniprot IDs			Q5W009 Q96I25
PDB IDs			2PE8 2PEH 5LSO 6HIP
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process MRNA Binding Spliceosomal Complex Regulation Of RNA Splicing Nucleoplasm Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleus Catalytic Step 2 Spliceosome Ribonucleoprotein Complex Post-transcriptional Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process MRNA 3'-UTR Binding Regulation Of RNA Stability MiRNA Binding Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of MRNA Stability MRNA Stabilization Regulation Of Translation TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation U2 SnRNP Positive Regulation Of Gene Expression Regulation Of Gene Expression Negative Regulation Of Translation Positive Regulation Of Cytoplasmic Translation Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process CRD-mediated MRNA Stabilization Positive Regulation Of Biosynthetic Process	RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Translation MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of Translation Extracellular Vesicle Regulation Of Rac Protein Signal Transduction Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Protein Metabolic Process Regulation Of Fat Cell Differentiation Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Gene Expression MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Cytokine Production Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Cell Cycle Regulation Of Macromolecule Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Catabolic Process Sin3-type Complex Negative Regulation Of Developmental Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Multicellular Organismal Process Regulation Of Protein Metabolic Process Negative Regulation Of Protein Catabolic Process Spermidine Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Necroptotic Process U11/U12 SnRNP Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Lipoprotein Transport Cellular Response To Resveratrol Negative Regulation Of Hydrogen Sulfide Biosynthetic Process Negative Regulation Of Endothelial Tube Morphogenesis Positive Regulation Of Replicative Senescence Negative Regulation Of Aortic Smooth Muscle Cell Differentiation
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