MIRLET7D and SPOUT1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIRLET7D	SPOUT1
Description		microRNA let-7d	SPOUT domain containing methyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex Extracellular Vesicle	Chromosome, Centromeric Region Kinetochore Chromosome Cytoplasm Centrosome Spindle Cytoskeleton Spindle Pole Centrosome Mitotic Spindle
	Molecular Function		RNA Binding Protein Binding Methyltransferase Activity Transferase Activity MiRNA Binding RRNA (uridine-N3-)-methyltransferase Activity S-adenosyl-L-methionine Binding
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing	RRNA Processing Post-transcriptional Regulation Of Gene Expression Methylation MiRNA Processing Cell Division Maintenance Of Centrosome Location RRNA Base Methylation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		100 interacting genes: AIMP1 APOBEC3B AQR ATXN2L C1QBP CDC5L CHERP CPSF6 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PRMT1 PTBP1 PUF60 PUM1 PURA QARS1 RARS1 RBM10 RBM12B RBM14 RBM4 RBM4B RBM5 RBM6 RTCB SAFB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SLTM SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	52 interacting genes: CSNK2B INCA1 MIR1-1 MIR106A MIR106B MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR34A MIR34B MIR429 MIR7-1 MIR9-1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT PLK1
Entrez ID		406886	51490
HPRD ID			12935
Ensembl ID		ENSG00000199133	ENSG00000198917
Uniprot IDs			Q5T280
PDB IDs			4RG1 8QSU 8QSV 8QSW
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Macromolecule Metabolic Process Nucleus Post-transcriptional Regulation Of Gene Expression Nucleoplasm MiRNA Binding Spliceosomal Complex Regulation Of MRNA Processing Ribonucleoprotein Complex Aminoacyl-tRNA Synthetase Multienzyme Complex Catalytic Step 2 Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Translation Cytoplasmic Stress Granule Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Stability Negative Regulation Of RNA Catabolic Process Regulation Of MRNA Stability Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of Primary Metabolic Process MRNA Stabilization Regulation Of Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Negative Regulation Of Translation TRNA Aminoacylation Nucleolus Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cytoplasmic Translation Positive Regulation Of Gene Expression	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle MRNA Destabilization Negative Regulation Of Translation RNA Destabilization Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cytokine Production Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of MRNA Stability Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Angiogenesis Regulation Of RNA Stability Negative Regulation Of Vasculature Development Negative Regulation Of Protein Metabolic Process Regulation Of Angiogenesis Regulation Of Cell Migration Regulation Of Vasculature Development Regulation Of Metabolic Process Regulation Of Cell Motility Regulation Of Translation Negative Regulation Of Multicellular Organismal Process Regulation Of Locomotion Negative Regulation Of Developmental Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of MRNA Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?