SPOUT1 and MIR93

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		SPOUT1	MIR93
Description		SPOUT domain containing methyltransferase 1	microRNA 93
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Chromosome Cytoplasm Centrosome Spindle Cytoskeleton Spindle Pole Centrosome Mitotic Spindle	Extracellular Space RISC Complex Extracellular Vesicle
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity Transferase Activity MiRNA Binding RRNA (uridine-N3-)-methyltransferase Activity S-adenosyl-L-methionine Binding	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	RRNA Processing Post-transcriptional Regulation Of Gene Expression Methylation MiRNA Processing Cell Division Maintenance Of Centrosome Location RRNA Base Methylation	Negative Regulation Of Cytokine Production Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Interleukin-8 Production MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Protein Secretion Negative Regulation Of Cholesterol Efflux Negative Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		52 interacting genes: CSNK2B INCA1 MIR1-1 MIR106A MIR106B MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR34A MIR34B MIR429 MIR7-1 MIR9-1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT PLK1	82 interacting genes: APOBEC3B C1QBP CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 PDCD11 PGAM5 PLRG1 PTBP1 PTBP3 PUM1 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBMS1 RBMS2 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRMT1L U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZNF106
Entrez ID		51490	407050
HPRD ID		12935
Ensembl ID		ENSG00000198917	ENSG00000207757
Uniprot IDs		Q5T280
PDB IDs		4RG1 8QSU 8QSV 8QSW
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle MRNA Destabilization Negative Regulation Of Translation RNA Destabilization Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cytokine Production Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of MRNA Stability Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Angiogenesis Regulation Of RNA Stability Negative Regulation Of Vasculature Development Negative Regulation Of Protein Metabolic Process Regulation Of Angiogenesis Regulation Of Cell Migration Regulation Of Vasculature Development Regulation Of Metabolic Process Regulation Of Cell Motility Regulation Of Translation Negative Regulation Of Multicellular Organismal Process Regulation Of Locomotion Negative Regulation Of Developmental Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of MRNA Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Nucleus MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex RNA Splicing, Via Transesterification Reactions Post-transcriptional Regulation Of Gene Expression Spliceosomal Complex Aminoacyl-tRNA Synthetase Multienzyme Complex MRNA 3'-UTR Binding Nucleoplasm Catalytic Step 2 Spliceosome Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Cytoplasmic Stress Granule Regulation Of MRNA Processing MiRNA Binding TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of MRNA Splicing, Via Spliceosome TRNA Aminoacylation Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization TRNA Metabolic Process Regulation Of RNA Stability MRNA Stabilization Regulation Of Gene Expression Nucleolus Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Stability Positive Regulation Of Cytoplasmic Translation Ligase Activity P-body CRD-mediated MRNA Stabilization Positive Regulation Of Gene Expression Negative Regulation Of Macromolecule Metabolic Process MRNA 5'-UTR Binding
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