MIRLET7D and IGF2BP1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIRLET7D	IGF2BP1
Description		microRNA let-7d	insulin like growth factor 2 mRNA binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex Extracellular Vesicle	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule Lamellipodium Filopodium Axon Dendrite Growth Cone Cell Projection Neuronal Cell Body Dendritic Spine Synapse Perinuclear Region Of Cytoplasm CRD-mediated MRNA Stability Complex Ribonucleoprotein Complex
	Molecular Function		Nucleic Acid Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Translation Regulator Activity MRNA 5'-UTR Binding N6-methyladenosine-containing RNA Reader Activity
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing	Regulation Of Cytokine Production RNA Localization Regulation Of Translation Nervous System Development Positive Regulation Of Cell Population Proliferation Regulation Of MRNA Stability Involved In Response To Stress Negative Regulation Of Translation Pallium Cell Proliferation In Forebrain MRNA Transport CRD-mediated MRNA Stabilization Neuronal Stem Cell Population Maintenance Dendrite Arborization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Cytoplasmic Translation
Pathways			Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS			Adult body size ( 32376654) Alcohol consumption ( 31358974) Alcohol use disorder (consumption score) ( 30940813) Body fat percentage ( 26833246) Brain morphology (MOSTest) ( 32665545) HDL cholesterol levels in HIV infection ( 33109212) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Primary tooth development (number of teeth) ( 20195514 23704328) Primary tooth development (time to first tooth eruption) ( 20195514 23704328) Prostate cancer ( 23535732) Waist circumference ( 31928498) Walking pace ( 33128006)
Interacting Genes		100 interacting genes: AIMP1 APOBEC3B AQR ATXN2L C1QBP CDC5L CHERP CPSF6 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PRMT1 PTBP1 PUF60 PUM1 PURA QARS1 RARS1 RBM10 RBM12B RBM14 RBM4 RBM4B RBM5 RBM6 RTCB SAFB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SLTM SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	82 interacting genes: ANXA1 BIRC2 CDC42 CEBPA CTNNB1 DUX4 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT UBXN7 USP7 WEE2-AS1
Entrez ID		406886	10642
HPRD ID			09752
Ensembl ID		ENSG00000199133	ENSG00000159217
Uniprot IDs			D3DTW3 Q9NZI8
PDB IDs			3KRM 6QEY
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Macromolecule Metabolic Process Nucleus Post-transcriptional Regulation Of Gene Expression Nucleoplasm MiRNA Binding Spliceosomal Complex Regulation Of MRNA Processing Ribonucleoprotein Complex Aminoacyl-tRNA Synthetase Multienzyme Complex Catalytic Step 2 Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Translation Cytoplasmic Stress Granule Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Stability Negative Regulation Of RNA Catabolic Process Regulation Of MRNA Stability Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of Primary Metabolic Process MRNA Stabilization Regulation Of Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Negative Regulation Of Translation TRNA Aminoacylation Nucleolus Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cytoplasmic Translation Positive Regulation Of Gene Expression	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization RNA Destabilization Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Migration Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Cytokine Production Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Cell Motility Regulation Of Angiogenesis Negative Regulation Of Locomotion Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Regulation Of Metabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Developmental Process Regulation Of Translation Negative Regulation Of Protein Metabolic Process Regulation Of MRNA Stability Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Regulation Of RNA Stability Regulation Of Cell Motility Regulation Of Endothelial Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Extracellular Space Regulation Of Locomotion Negative Regulation Of Signal Transduction Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?