CAB39 and STRADA

Number of citations of the paper that reports this interaction (PMID 15561763)
37

Data Source:
HPRD (in vivo, in vitro)

		CAB39	STRADA
Gene Name		calcium binding protein 39	STE20-related kinase adaptor alpha
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome Serine/threonine Protein Kinase Complex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity	Protein Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity
	Biological Process	Protein Phosphorylation Cell Cycle Arrest Insulin Receptor Signaling Pathway Positive Regulation Of Peptidyl-threonine Phosphorylation Signal Transduction By Phosphorylation Activation Of Protein Kinase Activity Positive Regulation Of Peptidyl-serine Phosphorylation Intracellular Signal Transduction Protein Heterooligomerization Cellular Hypotonic Response Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Rubidium Ion Transport Negative Regulation Of Rubidium Ion Transmembrane Transporter Activity	Mitotic Cell Cycle Protein Phosphorylation Protein Export From Nucleus Cell Cycle Arrest Insulin Receptor Signaling Pathway Activation Of Protein Kinase Activity Intracellular Signal Transduction Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways		Insulin receptor signalling cascade IRS-mediated signalling Regulation of AMPK activity via LKB1 mTOR signalling IRS-related events mTOR signalling IGF1R signaling cascade IRS-related events triggered by IGF1R IRS-mediated signalling Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Energy dependent regulation of mTOR by LKB1-AMPK PKB-mediated events PI3K Cascade PKB-mediated events PI3K Cascade Signaling by Insulin receptor	Insulin receptor signalling cascade IRS-mediated signalling Regulation of AMPK activity via LKB1 mTOR signalling IRS-related events mTOR signalling IGF1R signaling cascade IRS-related events triggered by IGF1R IRS-mediated signalling Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Energy dependent regulation of mTOR by LKB1-AMPK PKB-mediated events PI3K Cascade PKB-mediated events PI3K Cascade Signaling by Insulin receptor
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: PRKAA1 STK11 STRADA STRADB	3 interactors: CAB39 STK11 XPO1
Entrez ID		51719	92335
HPRD ID		10091	14332
Ensembl ID		ENSG00000135932	ENSG00000266173
Uniprot IDs		A8K8L7 Q9Y376	Q7RTN6 Q86YC8
PDB IDs		1UPK 1UPL 2WTK 3GNI 4FZA 4FZD 4FZF	1UPK 2WTK 3GNI
Enriched GO Terms of Interacting Partners?		Cell Cycle Arrest Insulin Receptor Signaling Pathway Cellular Response To Insulin Stimulus Activation Of Protein Kinase Activity Response To Insulin Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Negative Regulation Of Cell Cycle Response To Peptide Hormone Positive Regulation Of Protein Kinase Activity Cellular Response To Organonitrogen Compound Response To Peptide Positive Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Cellular Response To Hormone Stimulus Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Response To Organonitrogen Compound Positive Regulation Of Phosphorylation Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Cell Cycle Response To Hormone Cell Cycle Process Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Protein Phosphorylation Cell Cycle Protein Export From Nucleus Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Phosphorylation Cellular Response To Organic Substance Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Nuclear Export Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation TCR Signalosome Assembly Protein Heterooligomerization Response To UV Regulation Of Lipid Biosynthetic Process Regulation Of Signal Transduction	Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Cycle Protein Heterooligomerization Cell Cycle Arrest Insulin Receptor Signaling Pathway TCR Signalosome Assembly Regulation Of Cellular Response To Growth Factor Stimulus Cell Cycle Cellular Response To Insulin Stimulus Ribosomal Small Subunit Export From Nucleus Negative Regulation Of Rubidium Ion Transport Negative Regulation Of Rubidium Ion Transmembrane Transporter Activity Activation Of Protein Kinase Activity Response To Insulin Cellular Response To Organic Substance Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Regulation Of Rubidium Ion Transport Anoikis Regulation Of Protein Metabolic Process Regulation Of Cellular Amino Acid Metabolic Process Cellular Response To UV-B Ribosomal Large Subunit Export From Nucleus Organelle Localization Protein Oligomerization Negative Regulation Of Cell Cycle Response To Peptide Hormone Ribosomal Subunit Export From Nucleus Positive Regulation Of Protein Kinase Activity Cellular Response To Organonitrogen Compound Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Thymic T Cell Selection Response To Peptide Response To Organic Substance Positive Regulation Of Kinase Activity Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Transferase Activity Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Response To Hormone Stimulus Cellular Hypotonic Response Golgi Localization Positive Regulation Of Peptidyl-threonine Phosphorylation Response To UV-B Hypotonic Response Positive Regulation Of Gluconeogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Tagcloud ?		alterative apical becomes convoluted cotransporter dct dct1 displaced displaying exclusive hyperphosphorylated hypotension m025alpha medulla mo25alpha modestly ncc nkcc2 osr1 paralleled punctate redistributes spak spak2 sps ste20 thiazide tubule wnk1	200mg acetonitrile ammonium analyte ascending aspec automatic automatically c18 cartridges chronobiological circadian deviation gilson insomnia melatonin neu neup11 p11 phasing precision processor purospher put qcss quantification spe true xl
Tagcloud (Difference) ?		alterative apical becomes convoluted cotransporter dct dct1 displaced displaying exclusive hyperphosphorylated hypotension m025alpha medulla mo25alpha modestly ncc nkcc2 osr1 paralleled punctate redistributes spak spak2 sps ste20 thiazide tubule wnk1	200mg acetonitrile ammonium analyte ascending aspec automatic automatically c18 cartridges chronobiological circadian deviation gilson insomnia melatonin neu neup11 p11 phasing precision processor purospher put qcss quantification spe true xl
Tagcloud (Intersection) ?