CAB39 and STK24

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CAB39	STK24
Description		calcium binding protein 39	serine/threonine kinase 24
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Z Disc Protein-containing Complex Secretory Granule Lumen Extracellular Exosome Serine/threonine Protein Kinase Complex Ficolin-1-rich Granule Lumen	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Membrane Extracellular Exosome FAR/SIN/STRIPAK Complex
	Molecular Function	Protein Binding Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity Protein Serine/threonine Kinase Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Cadherin Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Signal Transduction Response To Activity Intracellular Signal Transduction Cellular Hypotonic Response Response To Thyroid Hormone Negative Regulation Of Potassium Ion Transmembrane Transport	Protein Phosphorylation Apoptotic Process Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Cellular Response To Starvation Negative Regulation Of Cell Migration Cellular Response To Oxidative Stress Intracellular Signal Transduction Protein Autophosphorylation Regulation Of Axon Regeneration Execution Phase Of Apoptosis
Pathways		Energy dependent regulation of mTOR by LKB1-AMPK Neutrophil degranulation	Apoptotic cleavage of cellular proteins Apoptotic execution phase
Drugs			Fostamatinib
Diseases
GWAS			Adult body size ( 32376654) Adventurousness ( 30643258) Alzheimer's disease ( 22159054) Educational attainment ( 23722424 25201988) Gastroesophageal reflux disease ( 34187846) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Household income (MTAG) ( 31844048) Longevity ( 20834067) Methadone dose in opioid dependence ( 28115739) Mood instability ( 31168069) Reading disability or specific language impairment (pleiotropy) ( 25065397) Shoulder impingement or rotator cuff tear ( 33482370) Triglyceride levels ( 32203549) Urinary sodium excretion ( 31409800)
Interacting Genes		13 interacting genes: CEBPA CEP44 GOLGA2 IPO5 MCCD1 MED7 PRKAA1 RSL1D1 SHMT2 STK11 STK24 STRADA STRADB	12 interacting genes: CAB39 CASP3 CASP7 CASP8 ERBB2 LRRK2 NEDD4 OGT PDCD10 STK11 STK38L VAV2
Entrez ID		51719	8428
HPRD ID		10091	10385
Ensembl ID		ENSG00000135932	ENSG00000102572
Uniprot IDs		Q9Y376	B4DR80 Q5U0E6 Q6P0Y1 Q9Y6E0
PDB IDs		1UPK 1UPL 2WTK 3GNI 4FZA 4FZD 4FZF 4NZW 4O27 8VSU	3A7F 3A7G 3A7H 3A7I 3A7J 3CKW 3CKX 3ZHP 4O27 4QML 4QMM 4QMN 4QMO 4QMP 4QMQ 4QMS 4QMT 4QMU 4QMV 4QMW 4QMX 4QMY 4QMZ 4QNA 4QO9 4U8Z 4W8D 4W8E 7B30 7B31 7B32 7B33 7B34 7B35 8BZI 8BZJ 8QLQ 8QLR 8QLS 8QLT
Enriched GO Terms of Interacting Partners?		Organelle Disassembly Serine/threonine Protein Kinase Complex Regulation Of Protein Metabolic Process Intracellular Protein-containing Complex Activation Of Protein Kinase Activity Negative Regulation Of Translational Initiation Negative Regulation Of Hepatocyte Apoptotic Process Protein Modification Process Positive Regulation Of Protein Metabolic Process Protein Metabolic Process Protein Kinase Activity G1 To G0 Transition Regulation Of Translational Initiation Macromolecule Metabolic Process Cadherin Binding Positive Regulation Of Phosphate Metabolic Process Negative Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Protein Modification Process Positive Regulation Of Protein Kinase Activity Protein Phosphorylation Positive Regulation Of Kinase Activity Negative Regulation Of Epithelial Cell Apoptotic Process Positive Regulation Of Protein Modification Process Phosphorylation Regulation Of Protein Localization To Nucleus Protein Export From Nucleus Regulation Of Translation Rescue Of Stalled Ribosome Intracellular Signal Transduction Negative Regulation Of Translation Protein Kinase Activator Activity Carbohydrate Homeostasis Macrophage Differentiation Glucose Homeostasis RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Dexamethasone Multicellular Organismal-level Homeostasis Centrosome Cycle Negative Regulation Of Glucosylceramide Biosynthetic Process L-allo-threonine Aldolase Activity Regulation Of Type I Interferon-mediated Signaling Pathway Ribosome Disassembly Negative Regulation Of Immune Response Response To Ketone Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Signal Transduction Positive Regulation Of Protein Phosphorylation Negative Regulation Of Immune System Process Regulation Of Protein Kinase Activity Regulation Of Immune Response	Positive Regulation Of Protein Metabolic Process Intracellular Signal Transduction Pyroptotic Inflammatory Response Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Execution Phase Of Apoptosis Regulation Of Intracellular Signal Transduction Regulation Of Cellular Localization Cytosol Regulation Of Protein Metabolic Process Signal Transduction Neuromuscular Junction Development Protein Modification Process Cellular Response To Staurosporine Response To UV Regulation Of Autophagy Protein Processing Response To Anesthetic Death-inducing Signaling Complex Cysteine-type Endopeptidase Activity Positive Regulation Of Neuron Apoptotic Process Apoptotic Process Positive Regulation Of Pyroptotic Inflammatory Response Protein Metabolic Process Cell Death Regulation Of Programmed Cell Death Programmed Cell Death Response To Cobalt Ion Cytoplasm Regulation Of Signal Transduction Fibroblast Apoptotic Process Regulation Of Intracellular Transport Heart Development Response To Stress Cell Projection Organization Protein Localization To Organelle Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Protein Modification Process Golgi Localization Protein Maturation Response To Light Stimulus Apoptotic Signaling Pathway Response To Metal Ion Death Receptor Binding Positive Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Protein Poly-ADP-ribosylation
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