LHB and CGA

Number of citations: 0 (PubMedID 7679977)
Data Source: HPRD (in vitro, in vivo)

		LHB	CGA
Name		luteinizing hormone subunit beta	glycoprotein hormones, alpha polypeptide
Structure		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Golgi Lumen Pituitary Gonadotropin Complex	Extracellular Region Extracellular Space Golgi Lumen Follicle-stimulating Hormone Complex Pituitary Gonadotropin Complex
	Molecular Function	Signaling Receptor Binding Hormone Activity Protein Binding	Hormone Activity Protein Binding Follicle-stimulating Hormone Activity
	Biological Process	Progesterone Biosynthetic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Male Gonad Development Hormone-mediated Signaling Pathway	Thyroid Hormone Generation G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Gonad Development Hormone-mediated Signaling Pathway Regulation Of Signaling Receptor Activity Positive Regulation Of Steroid Biosynthetic Process Positive Regulation Of Cell Migration Thyroid Gland Development Luteinizing Hormone Secretion Cellular Response To Hormone Stimulus Organ Growth Follicle-stimulating Hormone Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Organ Growth Follicle-stimulating Hormone Secretion Developmental Growth
Pathways		Androgen biosynthesis Mineralocorticoid biosynthesis Glycoprotein hormones Hormone ligand-binding receptors G alpha (s) signalling events Reactions specific to the complex N-glycan synthesis pathway	Androgen biosynthesis Mineralocorticoid biosynthesis Glycoprotein hormones Thyroxine biosynthesis Hormone ligand-binding receptors G alpha (s) signalling events TFAP2 (AP-2) family regulates transcription of growth factors and their receptors Reactions specific to the complex N-glycan synthesis pathway
GWAS		No GWAS studies recorded	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134 ) Atrial fibrillation ( 29892015 30061737 ) Thyroid stimulating hormone levels ( 32769997 )
Interacting Genes		7 interacting genes: CGA FHL3 GNAI2 GNAS LHCGR NTM SGTB	9 interacting genes: CGB3 CGB5 FSHB FSHR LHB LHCGR PTN PTPN12 TSHB
Entrez ID		3972	1081
HPRD ID		01072	00342
Ensembl ID		ENSG00000104826	ENSG00000135346
Uniprot IDs		A0A0F7RQE6 P01229	A0A087WYZ4 P01215 Q6I9S8
PDB IDs		Not available	1DZ7 1E9J 1FL7 1HCN 1HD4 1HRP 1QFW 1XWD 4AY9 4MQW 7FIG 7FIH 7FII 7T9I 7UTZ 7XW5 8I2G
GO Terms Enriched among Interactors		Guanyl Nucleotide Binding Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway G-protein Beta/gamma-subunit Complex Binding Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Heterotrimeric G-protein Complex Ovulation Cycle Process G Protein-coupled Receptor Signaling Pathway Cellular Response To Hormone Stimulus Choriogonadotropin Hormone Binding Choriogonadotropin Hormone Receptor Activity Luteinizing Hormone Receptor Activity Regulation Of Steroid Biosynthetic Process Follicle-stimulating Hormone Secretion Follicle-stimulating Hormone Activity Negative Regulation Of Developmental Growth Regulation Of Steroid Metabolic Process Follicle-stimulating Hormone Complex Mu-type Opioid Receptor Binding Luteinizing Hormone Signaling Pathway TRC Complex Regulation Of Hormone Levels Renal System Process Pituitary Gonadotropin Complex Follicle-stimulating Hormone Signaling Pathway Animal Organ Development Gonad Development Development Of Secondary Male Sexual Characteristics Luteinizing Hormone Secretion Response To Hormone Hormone-mediated Signaling Pathway Corticotropin-releasing Hormone Receptor 1 Binding Adenylate Cyclase Regulator Activity Positive Regulation Of Inositol Trisphosphate Biosynthetic Process Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Hair Follicle Placode Formation Adenylate Cyclase Activator Activity Adenylate Cyclase-activating Serotonin Receptor Signaling Pathway Cellular Response To Luteinizing Hormone Stimulus Regulation Of Inositol Trisphosphate Biosynthetic Process Cellular Response To Peptide Hormone Stimulus Gonadotropin Secretion Regulation Of Lipid Biosynthetic Process Reproductive Structure Development Beta-2 Adrenergic Receptor Binding Development Of Secondary Sexual Characteristics D1 Dopamine Receptor Binding Response To Luteinizing Hormone Negative Regulation Of Growth Rhythmic Process Positive Regulation Of Urine Volume	Female Gamete Generation Hormone Activity Hormone-mediated Signaling Pathway G Protein-coupled Receptor Signaling Pathway Pituitary Gonadotropin Complex Follicle-stimulating Hormone Signaling Pathway Ovulation Cycle Process Ovarian Follicle Development Progesterone Biosynthetic Process Gamete Generation Sertoli Cell Proliferation Rhythmic Process Protein-hormone Receptor Activity C21-steroid Hormone Biosynthetic Process Reproductive Process Progesterone Metabolic Process Male Gonad Development Signaling Receptor Binding Developmental Process Involved In Reproduction Gonad Development Cellular Response To Gonadotropin Stimulus Uterus Development C21-steroid Hormone Metabolic Process Female Gonad Development Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Steroid Hormone Biosynthetic Process Response To Gonadotropin Regulation Of Hormone Levels Reproductive Structure Development Ketone Biosynthetic Process Regulation Of Hormone Metabolic Process Hormone Biosynthetic Process Regulation Of Bone Resorption G Protein-coupled Peptide Receptor Activity Regulation Of Bone Remodeling Tissue Regeneration Extracellular Space Follicle-stimulating Hormone Receptor Activity Regulation Of Acetylcholine Metabolic Process Choriogonadotropin Hormone Binding Choriogonadotropin Hormone Receptor Activity Luteinizing Hormone Receptor Activity Regulation Of Osteoclast Differentiation Regulation Of Tissue Remodeling Regulation Of Steroid Biosynthetic Process Developmental Growth Steroid Biosynthetic Process Ketone Metabolic Process Follicle-stimulating Hormone Activity Follicle-stimulating Hormone Complex