CGA and CGB

Number of citations of the paper that reports this interaction (PMID 8202136)
63

Data Source:
HPRD (in vitro)

		CGA	CGB
Gene Name		glycoprotein hormones, alpha polypeptide	chorionic gonadotropin, beta polypeptide
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region	Extracellular Region
	Molecular Function	Hormone Activity Protein Binding	Hormone Activity
	Biological Process	Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Proliferation Peptide Hormone Processing Positive Regulation Of Cell Migration Cellular Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter	Apoptotic Process Signal Transduction Cell-cell Signaling Female Gamete Generation Peptide Hormone Processing Cellular Protein Metabolic Process
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Amine-derived hormones Metabolism of lipids and lipoproteins Mineralocorticoid biosynthesis G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Androgen biosynthesis Metabolism of amino acids and derivatives Metabolism of steroid hormones and vitamin D Peptide hormone metabolism GPCR downstream signaling Glycoprotein hormones Thyroxine biosynthesis Peptide hormone biosynthesis	Peptide hormone metabolism Glycoprotein hormones Peptide hormone biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CGB CGB5 FSHB LHB LHCGR PTN PTPN12 TSHB	4 interactors: APP CGA FSHB LHCGR
Entrez ID		1081	1082
HPRD ID		00342	00343
Ensembl ID		ENSG00000135346	ENSG00000104827
Uniprot IDs		P01215 Q6I9S8	P01233
PDB IDs		1DZ7 1E9J 1FL7 1HCN 1HD4 1HRP 1QFW 1XUL 1XWD 4AY9	1HCN 1HRP 1QFW 1XUL
Enriched GO Terms of Interacting Partners?		Peptide Hormone Processing Peptide Metabolic Process Hormone Metabolic Process Protein Processing Cellular Amide Metabolic Process Regulation Of Hormone Levels Female Gamete Generation Progesterone Biosynthetic Process Male Gonad Development Single Organism Reproductive Process Progesterone Metabolic Process C21-steroid Hormone Biosynthetic Process Reproductive Process Male Sex Differentiation C21-steroid Hormone Metabolic Process Gonad Development Development Of Primary Sexual Characteristics Sex Differentiation Cell-cell Signaling Hormone Biosynthetic Process Signal Transduction Signaling Cell Communication Cellular Ketone Metabolic Process Reproductive Structure Development Reproductive System Development Steroid Biosynthetic Process Cellular Protein Metabolic Process Cellular Response To Stimulus Luteinizing Hormone Signaling Pathway Gamete Generation Developmental Process Involved In Reproduction Positive Regulation Of Inositol Trisphosphate Biosynthetic Process Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Follicle-stimulating Hormone Signaling Pathway Sertoli Cell Proliferation Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Protein Metabolic Process Steroid Metabolic Process Regulation Of Inositol Trisphosphate Biosynthetic Process Response To Stimulus Positive Regulation Of Inositol Phosphate Biosynthetic Process Reproduction Cognition Positive Regulation Of CAMP-mediated Signaling G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Bone Resorption Regulation Of CAMP-mediated Signaling	Peptide Hormone Processing Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Peptide Metabolic Process Male Gonad Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Hormone Metabolic Process Male Sex Differentiation Positive Regulation Of Metabolic Process Collateral Sprouting In Absence Of Injury Luteinizing Hormone Signaling Pathway Gonad Development Development Of Primary Sexual Characteristics Protein Processing Steroid Metabolic Process Reproductive Process Cellular Amide Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Hormone Levels Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Inositol Trisphosphate Biosynthetic Process Cognition Sex Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Axon Choice Point Recognition Follicle-stimulating Hormone Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Sertoli Cell Proliferation Neuron Remodeling Regulation Of Inositol Trisphosphate Biosynthetic Process Positive Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of CAMP-mediated Signaling Signal Transduction Progesterone Biosynthetic Process Reproductive Structure Development Reproductive System Development Positive Regulation Of Bone Resorption Cellular Copper Ion Homeostasis Signaling Cell Communication Regulation Of Cell Migration
Tagcloud ?		aberrations arginine codon documented encode faulty finger fingers gonads hotspot mesothelium mobility mutational nonsense spleen sscp stop strand substituted tga tumours urogenital uterus wilms wt wt1 wts zf3 zinc	apoc2 atp1a3 bckdha cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39 tnnt1
Tagcloud (Difference) ?		aberrations arginine codon documented encode faulty finger fingers gonads hotspot mesothelium mobility mutational nonsense spleen sscp stop strand substituted tga tumours urogenital uterus wilms wt wt1 wts zf3 zinc	apoc2 atp1a3 bckdha cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39 tnnt1
Tagcloud (Intersection) ?