SIGLEC11

Description		sialic acid binding Ig like lectin 11
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Phosphatase Binding Carbohydrate Binding Sialic Acid Binding
	Biological Process	Cell Adhesion
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Lung cancer in never smokers ( 28604730)
Interacting Genes		3 interacting genes: LGALS3BP PTPN11 PTPN6
Entrez ID		114132
HPRD ID		06196
Ensembl ID		ENSG00000161640
Uniprot IDs		Q96RL6
PDB IDs
Enriched GO Terms of Interacting Partners?		Non-membrane Spanning Protein Tyrosine Phosphatase Activity Negative Regulation Of Neutrophil Activation Regulation Of Neutrophil Activation Neutrophil Activation Involved In Immune Response Peptidyl-tyrosine Dephosphorylation Platelet Formation Megakaryocyte Development Regulation Of Lipopolysaccharide-mediated Signaling Pathway Neutrophil Activation Regulation Of Type I Interferon-mediated Signaling Pathway Phosphotyrosine Residue Binding T Cell Costimulation Regulation Of Cell Adhesion Mediated By Integrin Myeloid Cell Development Negative Regulation Of T Cell Proliferation Protein Dephosphorylation Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Cell Adhesion Molecule Binding Protein Tyrosine Phosphatase Activity Negative Regulation Of Leukocyte Proliferation Dephosphorylation Myeloid Leukocyte Activation Epididymis Development Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Phosphoprotein Phosphatase Activity Negative Regulation Of T Cell Activation Leukocyte Activation Involved In Immune Response Negative Regulation Of Leukocyte Cell-cell Adhesion Cell Activation Involved In Immune Response Negative Regulation Of Lymphocyte Activation Regulation Of Tumor Necrosis Factor Production Hemopoiesis Regulation Of Cytokine-mediated Signaling Pathway Regulation Of T Cell Proliferation Intestinal Epithelial Cell Migration Negative Regulation Of Leukocyte Activation Negative Regulation Of Cell-cell Adhesion Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Cell Activation Cerebellar Cortex Formation Regulation Of Mononuclear Cell Proliferation Myeloid Cell Differentiation Positive Regulation Of T Cell Activation Negative Regulation Of Mast Cell Activation Involved In Immune Response Negative Regulation Of Glucocorticoid Secretion Regulation Of Leukocyte Proliferation Regulation Of ERK1 And ERK2 Cascade CD27 Signaling Pathway
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