FKBP6 and CFP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FKBP6	CFP
Description		FKBP prolyl isomerase family member 6 (inactive)	complement factor properdin
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GO Annotations	Cellular Component	Synaptonemal Complex Fibrillar Center Nucleus Cytoplasm Cytosol Microtubule Cytoskeleton Intercellular Bridge	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule Specific Granule Lumen Cytoplasmic Side Of Golgi Membrane Tertiary Granule Lumen
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Identical Protein Binding Hsp90 Protein Binding	Protein Binding
	Biological Process	Protein Folding Spermatogenesis Cell Differentiation Regulatory NcRNA-mediated Gene Silencing PiRNA Processing Positive Regulation Of Viral Genome Replication Meiotic Cell Cycle Transposable Element Silencing By PiRNA-mediated DNA Methylation	Immune System Process Immune Response Complement Activation Complement Activation, Alternative Pathway Defense Response To Bacterium Innate Immune Response Positive Regulation Of Complement Activation, Alternative Pathway Positive Regulation Of Immune Response Protein Stabilization Positive Regulation Of Opsonization
Pathways		Meiotic synapsis PIWI-interacting RNA (piRNA) biogenesis	Alternative complement activation Activation of C3 and C5 Defective B3GALTL causes PpS O-glycosylation of TSR domain-containing proteins Neutrophil degranulation Regulation of Complement cascade
Drugs
Diseases			Alternative complement pathway component defects, including the following four diseases: Factor B deficiency; Factor D deficiency; Factor H deficiency; Properdin deficiency
GWAS		Height ( 31562340) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		38 interacting genes: ACD ALDH3A1 CCDC198 CCNK CDK5RAP3 CFP CFTR CRACR2A DDIT4L DLGAP4 ECM1 EEF1D ENKD1 FAM107A GAPDH GSC2 HSP90AA1 IHO1 KANK2 KRT75 LZTS2 MAP3K1 MEI4 MEOX2 NME7 NTAQ1 PIAS2 PICK1 RAB11FIP2 RNF4 SAXO4 SUMO1P1 TEPSIN TINF2 TMEM9B TRIM55 TRIM63 ZNF655	33 interacting genes: BANF2 C3 CFAP206 CFB CYSRT1 FHL5 FKBP6 GEMIN4 GNE HEXIM2 HOXA1 KCTD9 KLHL38 KRTAP11-1 KRTAP12-2 KRTAP3-1 KRTAP6-2 LCE1A LONRF1 MID2 MTOR NEK6 NOXA1 PRKAB2 RECK SMARCC1 SPAG8 STK16 TRIP13 TXN VENTX ZNF330 ZNF414
Entrez ID		8468	5199
HPRD ID		05326	02308
Ensembl ID		ENSG00000077800	ENSG00000126759
Uniprot IDs		O75344	A0A0S2Z4I5 P27918
PDB IDs		3B7X	1W0R 1W0S 6RUR 6RUS 6RUV 6RV6 6S08 6S0A 6S0B 6SEJ 7B26 7NOZ 8Q6R
Enriched GO Terms of Interacting Partners?		Shelterin Complex Telomere Assembly Meiotic DNA Double-strand Break Formation Protein Binding Regulation Of Telomere Maintenance Via Telomerase Nuclear Telomere Cap Complex Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Localization To Chromosome, Telomeric Region
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