BNIP5 and BCL2L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BNIP5	BCL2L2
Description		BCL2 interacting protein 5	BCL2 like 2
Image
GO Annotations	Cellular Component		Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane Mitochondrial Membrane Bcl-2 Family Protein Complex
	Molecular Function	Protein Binding	Protein Binding Channel Activity Identical Protein Binding Disordered Domain Specific Binding
	Biological Process		Release Of Cytochrome C From Mitochondria Developmental Process Involved In Reproduction Apoptotic Process Spermatogenesis Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Transmembrane Transport Sertoli Cell Proliferation Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Drugs			Navitoclax
Diseases
GWAS			Height ( 28552196) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		3 interacting genes: BCL2L1 BCL2L2 BNIP2	53 interacting genes: ANKS6 APOC1 APOC2 APOC4 ATP5PF BAD BAK1 BBC3 BCL2L11 BHLHA9 BID BIK BMF BNIP3 BNIP5 C10orf67 CD79A CEBPA CHODL CIDEB CISD2 CLDN7 ERVFRD-1 FATE1 G0S2 GORAB GPR151 GPX8 HRK KASH5 KCNJ6 LMNA LRRIQ1 MGST2 MUC1 PANX1 PPP1CA PSCA RHBDD2 S100B SAR1A SGPL1 SLC35E3 SLC35H1 SLC39A2 SLC39A6 STOM SUSD3 TCF4 TEX11 TMEM139 TMX1 TP53
Entrez ID		389384	599
HPRD ID		16824	03569
Ensembl ID		ENSG00000189325	ENSG00000129473
Uniprot IDs		P0C671	Q92843
PDB IDs		8IGC	1MK3 1O0L 1ZY3 2Y6W 4CIM
Enriched GO Terms of Interacting Partners?		Bcl-2 Family Protein Complex Release Of Cytochrome C From Mitochondria Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Channel Activity Apoptotic Mitochondrial Changes Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cell Death Extrinsic Apoptotic Signaling Pathway Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Programmed Cell Death Apoptotic Process In Bone Marrow Cell Epithelial Cell Proliferation Mitochondrial Membrane Intrinsic Apoptotic Signaling Pathway Mitochondrial Outer Membrane Dendritic Cell Proliferation Dendritic Cell Apoptotic Process Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Mitochondrion Organization Response To Cycloheximide Apoptotic Signaling Pathway BH3 Domain Binding Sertoli Cell Proliferation Negative Regulation Of Dendritic Cell Apoptotic Process Negative Regulation Of Execution Phase Of Apoptosis Response To Oxygen-glucose Deprivation Male Gamete Generation Spermatogenesis Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Spindle Pole Centrosome Positive Regulation Of Programmed Cell Death Hepatocyte Apoptotic Process Negative Regulation Of Release Of Cytochrome C From Mitochondria Gamete Generation Positive Regulation Of Apoptotic Process Ectopic Germ Cell Programmed Cell Death Negative Regulation Of Anoikis Negative Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Membrane Permeability Programmed Cell Death Involved In Cell Development Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Anoikis Disordered Domain Specific Binding Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Mitochondrion Organization Apoptotic Mitochondrial Changes Apoptotic Process Positive Regulation Of Apoptotic Process Release Of Cytochrome C From Mitochondria Cell Death Positive Regulation Of Programmed Cell Death Programmed Cell Death Mitochondrial Outer Membrane Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Apoptotic Signaling Pathway Regulation Of Membrane Permeability Mitochondrion Organization Cellular Response To Stress Regulation Of Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Protein-containing Complex Assembly Regulation Of Programmed Cell Death Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Fibroblast Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Intrinsic Apoptotic Signaling Pathway Mitochondrial Membrane Organization Positive Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of Intrinsic Apoptotic Signaling Pathway T Cell Apoptotic Process Bcl-2 Family Protein Complex Positive Regulation Of Organelle Organization Positive Regulation Of Fibroblast Apoptotic Process Cellular Response To Hypoxia Lymphocyte Apoptotic Process Thymocyte Apoptotic Process Cellular Response To Decreased Oxygen Levels Regulation Of Protein-containing Complex Assembly Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Triglyceride Metabolic Process Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Oxygen Levels Positive Regulation Of T Cell Apoptotic Process Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Identical Protein Binding Leukocyte Apoptotic Process Regulation Of IRE1-mediated Unfolded Protein Response Mitochondrion Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?