KRTAP26-1 and TRIP6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KRTAP26-1	TRIP6
Description		keratin associated protein 26-1	thyroid hormone receptor interactor 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Stress Fiber Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Anchoring Junction
	Molecular Function	Structural Molecule Activity Protein Binding	RNA Binding Interleukin-1 Receptor Binding Protein Binding Kinase Binding Metal Ion Binding Nuclear Thyroid Hormone Receptor Binding
	Biological Process		Cell Adhesion Signal Transduction Positive Regulation Of Cell Migration Chordate Embryonic Development Focal Adhesion Assembly Positive Regulation Of Non-canonical NF-kappaB Signal Transduction
Pathways		Keratinization
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Nonunion in individuals with fractures ( 30680360) Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		93 interacting genes: ACTMAP ACY3 ARID5A CARD10 CCNJL CELF5 CERCAM CFAP206 CFTR COL8A1 CYSRT1 DAZAP2 DTX2 EFEMP2 FAM168B FAM222B GDPD5 GRN HGS HNF1B HOXA1 ID3 INTS11 KRT34 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP13-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-7 KRTAP5-6 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 KRTAP9-2 KRTAP9-8 LASP1 LCE2B MAPKBP1 MGAT5B NBPF19 NHLRC4 NOTCH2NLA OTX1 PITX1 PLA2G10 PM20D2 PRR22 PRR35 PSMA3 RASD1 RBPMS RECK RHOXF2 RNF208 SF1 SIVA1 SLC15A2 SMARCC1 SMUG1 SPAG8 SPATA12 SPMIP9 SSC4D STK16 TEKT3 TEKT4 TENT5A TFAP2D TFG TOX TRIM42 TRIP13 TRIP6 VASN VENTX YTHDF1 ZNF34	164 interacting genes: ABI2 ADAMTSL4 AQP1 ARNT2 ATN1 ATP23 ATP5PO ATXN1 AXIN1 BAG3 BCAR1 BEX2 BYSL C11orf87 CATSPER1 CBLC CCDC120 CCDC187 CCDC24 CCL5 CEP57L1 CNTF CREB5 CRYBA4 CTAG2 DHX37 DMRT3 DTX2 EFHC1 EPDR1 ERBB2 EXOC3-AS1 FAM124B FAM222B FARS2 FAS FASLG FHL3 FOXD4L1 FRS3 GAD1 GATA1 GFI1B GLIS3 GNAI2 GNE GPS2 GSE1 HCK HLA-DPB1 HOXA1 HOXA9 HOXB9 HOXC8 HYKK IL16 ILF3 INCA1 IP6K3 IQCN ITGB4 KCTD9 KIF1A KIR2DL4 KLK15 KPRP KRTAP26-1 LMO2 LNX1 LPAR2 MAPKBP1 MEMO1 METTL17 MIEN1 MIIP MISP MSRB3 MVP NCK2 NEDD9 NEU4 NOL4L-DT NR1D2 NSMF NUP210 ODF1 OIP5 OTUB2 OTX1 PATZ1 PDGFRB PDLIM4 PER1 PIGS PIN1 PLEKHN1 POM121 POM121L4P PPDPF PPP1R16A PRKAA1 PRKAA2 PTK2 PTPN13 PTPN14 PXN RAD23A RANBP3L RERE RFX3 RHOA RHOQ RNF213 RNF214 SAXO1 SCAND1 SCRIB SETDB1 SHISA6 SIK3 SLC25A6 SMAD1 SMG9 SNAI1 SON SRC STAC STK16 SVIL SYNGAP1 TAB1 TBC1D22B TCAF1 TEKT4 TENT5C THRB TIE1 TLE5 TLR2 TMSB4X TPM3 TPM4 TRAF3IP2 TRAPPC2L TRIM29 TSGA10IP TSSK3 TTC23 TTLL10 TXN2 TXNDC5 USP2 VASN VCL WT1-AS YAP1 YPEL3 ZBP1 ZIC1 ZNF541 ZNF580 ZNF581 ZNF688 ZNF785
Entrez ID		388818	7205
HPRD ID		14206	04242
Ensembl ID		ENSG00000197683	ENSG00000087077
Uniprot IDs		Q6PEX3	Q15654
PDB IDs			1X61 2DLO
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Axonemal A Tubule Inner Sheath Hair Cycle Protein Binding	Protein Binding Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Signal Complex Assembly Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Cell Surface Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Peptidyl-tyrosine Phosphorylation Positive Regulation Of Metabolic Process Focal Adhesion Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Stress Fiber Actin Filament Cell Motility Positive Regulation Of Macromolecule Metabolic Process Anchoring Junction Positive Regulation Of RNA Metabolic Process Actin Filament Organization Sequence-specific Double-stranded DNA Binding Cell Migration Nucleus Cytoskeleton Necroptotic Signaling Pathway Cytoplasm Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity ERBB Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Transcription Regulator Complex Anatomical Structure Morphogenesis Regulation Of Protein Localization To Nucleus Regulation Of Protein Localization RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Mesoderm Development Positive Regulation Of TOR Signaling Positive Regulation Of Locomotion Regulation Of Locomotion Positive Regulation Of Phosphate Metabolic Process Protein Tyrosine Kinase Activity Cold Acclimation Regulation Of RNA Metabolic Process Regulation Of Podosome Assembly Supramolecular Fiber Organization Regulation Of Cell Motility Positive Regulation Of Cell Migration Cell Cortex
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