KRT13 and EIF4E2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KRT13	EIF4E2
Description		keratin 13	eukaryotic translation initiation factor 4E family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	P-body Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding MRNA Cap Binding
	Biological Process	Morphogenesis Of An Epithelium Cytoskeleton Organization Epithelial Cell Differentiation Regulation Of Translation In Response To Stress Intermediate Filament Organization	Translation Translational Initiation Regulation Of Translation Negative Regulation Of Translation Regulatory NcRNA-mediated Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Translational Initiation Type I Interferon-mediated Signaling Pathway Negative Regulation Of Type I Interferon-mediated Signaling Pathway Rescue Of Stalled Ribosome
Pathways		Keratinization Formation of the cornified envelope	ISG15 antiviral mechanism
Drugs
Diseases		White sponge nevus
GWAS			Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520) Refractive error ( 32231278)
Interacting Genes		70 interacting genes: ABI2 ABI3 AIRIM AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf216 CATSPERT CCHCR1 CCNC CEP57 CEP57L1 CFTR DES DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GLYCTK GOLGA8EP GRAP2 HGS HOOK3 IFT20 KLC3 KLC4 KRT1 KRT2 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT85 LSM2 MOS MYH1 MYO15B NEFL NEIL3 PPP1R18 PSMA1 PSMB1 PSMB2 RTL8B SGF29 SPG21 TLE5 TMSB4X TRIM42 TSG101 TXLNA TXLNB ZNF688	46 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 ARIH2 CARD9 CBY2 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MGAT5B MIPOL1 MYOG NECAB2 NOTCH2NLA PRDM14 REL SPAG5 SPRY2 TADA2A TCF4 TLE5 TMCC2 TRIM27 TRIM54 UBC UBXN11 USHBP1 USP54 ZBTB9
Entrez ID		3860	9470
HPRD ID		01016	05798
Ensembl ID		ENSG00000171401	ENSG00000135930
Uniprot IDs		A1A4E9 P13646	A0A8I5KSA5 B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1
PDB IDs			2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Intermediate Filament Cytoskeleton Cytosol Structural Constituent Of Cytoskeleton Intermediate Filament Polymerization Or Depolymerization Extracellular Exosome Cytoskeleton Cytoplasm Protein Binding Proteasome Core Complex Epidermis Development Actin-based Cell Projection	Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Protein Binding Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytoskeleton Organization Protein Serine/threonine Kinase Binding Identical Protein Binding Supramolecular Fiber Organization Microtubule End Structural Molecule Activity Eukaryotic Initiation Factor 4E Binding Negative Regulation Of Protein Localization To Nucleus Morphogenesis Of An Epithelium
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