C3orf62 and KRT3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C3orf62	KRT3
Description		chromosome 3 open reading frame 62	keratin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Spermatogenesis Cell Differentiation	Epithelial Cell Differentiation Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases			Meesmann corneal dystrophy
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Depression ( 33859377) Inflammatory bowel disease ( 28067908) Red cell distribution width ( 27863252) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		11 interacting genes: APP BFSP2 DGCR6 HAUS1 ING5 KRT3 LMNTD2 MRFAP1 MRFAP1L1 RFPL3 TXNDC9	41 interacting genes: BPIFA1 C3orf62 CCDC197 DEUP1 HAUS1 HGS HYI KIFC3 KRT13 KRT14 KRT15 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRTAP13-2 LHX3 LURAP1 NUP62 OIP5 PLEKHG4 SAPCD2 SPAG5 TRAF1 TRIM27 TRIM54 WASHC1 WWOX ZNF426
Entrez ID		375341	3850
HPRD ID		13475	01013
Ensembl ID		ENSG00000188315	ENSG00000186442
Uniprot IDs		Q6ZUJ4	P12035
PDB IDs
Enriched GO Terms of Interacting Partners?			Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Supramolecular Fiber Organization Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Anatomical Structure Morphogenesis Organelle Organization Cell Differentiation Cellular Developmental Process Cytosol Extracellular Exosome Structural Constituent Of Cytoskeleton Hair Cycle Developmental Process Epidermis Development Protein Binding Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Intermediate Filament Cytoskeleton Regulation Of Microtubule Cytoskeleton Organization Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Microtubule Organizing Center Organization Regulation Of Cytoskeleton Organization Actin Nucleation Centriole Assembly Hydroxypyruvate Isomerase Activity Symmetric Cell Division Negative Regulation Of Protein Localization To Cell Cortex
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