CCDC197 and FMNL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

		CCDC197	FMNL2
Description		coiled-coil domain containing 197	formin like 2
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol
	Molecular Function	Protein Binding	Actin Binding Small GTPase Binding Cadherin Binding Actin Filament Binding
	Biological Process		Cytoskeleton Organization Regulation Of Cell Shape Cell Migration Regulation Of Cell Morphogenesis Actin Cytoskeleton Organization Cortical Actin Cytoskeleton Organization
Pathways			RHO GTPases Activate Formins RHOC GTPase cycle CDC42 GTPase cycle
Drugs
Diseases
GWAS		Fish consumption ( 32895509)	Asthma (childhood onset) ( 27611488) Corneal astigmatism ( 30306274) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 29891935 33627673) Heel bone mineral density ( 30598549) Intraocular pressure ( 29235454 29617998 29785010 30054594 31959993) Lymphocyte count ( 32888494) Refractive astigmatism ( 30306274) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) White blood cell count ( 32888494)
Interacting Genes		19 interacting genes: BEX2 C1orf216 CCDC146 CCHCR1 CFTR CYTH4 DISC1 FMNL2 KRT3 KRT75 LCA5L NTAQ1 NXF1 RUNX1T1 SKA1 SMARCD1 TXN2 USHBP1 WASHC3	15 interacting genes: AP1B1 AP2B1 APP CCDC197 CDC42 KRT27 LCOR MIPOL1 NECAB1 NRIP1 PKNOX1 PNMA1 PRPF40A SUOX TTC3
Entrez ID		256369	114793
HPRD ID		12651	13545
Ensembl ID		ENSG00000175699	ENSG00000157827
Uniprot IDs		A0A1B0GUF5 A0A1W2PPK9	Q96PY5
PDB IDs			4YC7
Enriched GO Terms of Interacting Partners?
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