KRT2 and KRT33B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT2	KRT33B
Description		keratin 2	keratin 33B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Extracellular Space Nucleus Cytoplasm Cytosol Intermediate Filament Membrane Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Extracellular Space Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Keratinocyte Development Epidermis Development Peptide Cross-linking Keratinization Keratinocyte Activation Keratinocyte Proliferation Intermediate Filament Organization Positive Regulation Of Epidermis Development Keratinocyte Migration	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Hair Cycle Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Copper Anthralin Zinc acetate
Diseases		Ichthyosis bullosa of Siemens
GWAS
Interacting Genes		20 interacting genes: EVPL KRT13 KRT24 KRT25 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 OGT RNF26 SIRPA SMAD3	61 interacting genes: ABI2 AIMP2 AQP1 ARFIP1 ATG9A C1orf216 CCDC24 CNNM3 COX5B CYSRT1 DES DTNB DUSP21 FASLG FRS3 GOLGA6L2 GSTP1 HAPLN2 HDAC4 HGS HOXA1 INCA1 KDM1A KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LMO4 MOS NUP54 NUP58 PATZ1 PPP1R18 RAB26 RAMAC RTP5 RUNX1T1 SCNM1 SGF29 SHC3 USP2 VPS37C
Entrez ID		3849	3884
HPRD ID		02560	04136
Ensembl ID		ENSG00000172867	ENSG00000131738
Uniprot IDs		P35908	Q14525
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Organization Keratin Filament Intermediate Filament Structural Molecule Activity Epithelial Cell Differentiation Morphogenesis Of An Epithelium Tissue Morphogenesis Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Cytoskeleton Anatomical Structure Morphogenesis Cellular Developmental Process Cell Differentiation Extracellular Exosome Developmental Process Cytosol Hair Follicle Morphogenesis Epidermis Development Intermediate Filament Cytoskeleton Hair Cycle Process Hair Cycle Tissue Development Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Nitric Oxide Biosynthetic Process Cellular Response To Interleukin-12 Cellular Response To Glucose Stimulus	Intermediate Filament Organization Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Keratin Filament Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Protein Binding Epidermis Development Intermediate Filament Cytoskeleton Extracellular Exosome Cornified Envelope Tissue Development Developmental Process Structural Constituent Of Cytoskeleton
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